Varicella-Zoster Virus: Practice Essentials, Background, Pathophysiology

Furuta Y, Fukuda S, Suzuki S, et al. Detection of varicella-zoster virus DNA in Patients With acute peripheral facial palsy by the polymerase chain reaction, and Its use for early diagnosis of zoster sine herpete. J Med Virol. 1997 July 52 (3):. 316-9. [Medline]. Centers for Disease Control and Prevention (CDC Updated Recommendations for use of VariZIG – United States, 2013. Available at Accessed http://www. cdc. gov/mmwr/preview/mmwrhtml/mm6228a4. htm? s_cid=mm6228a4_w. July.

23, 2013. Shapiro ED, Vazquez M, Esposito D, Holabird N, Steinberg SP, Dziura J, et al. Effectiveness of 2 doses of varicella vaccine in children. J Infect Dis. 2011 Feb 1. 203 (3): 312-5. [Medline]. BA Pahud, Glaser CA, CL Dekker, Arvin AM, Schmid DS. Varicella zoster disease of the Central nervous system: epidemiological, clinical, and laboratory features 10 years after the introduction of the varicella vaccine. J Infect Dis. 2011 Feb 1. 203 (3): 316-23. [Medline].

Brink AA, van Gelder M, Wolffs PF, Bruggeman CA, van Loo IH. Compartmentalization of acyclovir-resistant varicella zoster virus: Implications for sampling in molecular diagnostics. Clin Infect Dis. 2011 Apr 15 52 (8): 982-7. [Medline]. Kubeyinje EP. Cost-benefit of oral acyclovir in the treatment of herpes zoster. Int J Dermatol. 1997 June 36 (6):. 457-9. [Medline]. T. Ready Varicella-Zoster Virus Globulin: New CDC Recommendations.

Medscape Medical News. Available at http://www. medscape. com/viewarticle/808220. Accessed: July 30, 2013. Updated Recommendations for Use of VariZIG – United States, 2013. MMWR Morb Mortal Wkly Rep 2013 Jul 19 62 (28): 574-6. . [Medline]. Dworkin RH, RL Barbano, Tyring SK, Betts RF, McDermott MP, Pennella-Vaughan J, et al. A randomized, placebo-controlled trial of oxycodone and of gabapentin for acute pain in herpes zoster. Pain. 2009 Apr.

142 (3): 209-17. [Medline]. Klein NP, Fireman B, Yih WK, Lewis E, Kulldorff M, Ray P, et al. Measles-mumps-rubella-varicella combination vaccine and the risk of febrile seizures. Pediatrics. 2010 Jul 126 (1):. E1-8. [Medline]. Hviid A. Measles-mumps-rubella-varicella vaccine combination Increases risk of febrile seizure. J Pediatr. Jan. 2011 158 (1): 170.

[Medline]. [Full Text]. [Guideline] Marin M, Broder KR, Temte JL Snider DE, Seward JF. Use of combination measles, mumps, rubella, and varicella vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2010 May 7. 59: 1-12. . [Medline]. [Full Text]. Tseng HF, Smith N, R Harpaz, et al. Herpes zoster vaccine in older adults and the risk of subsequent disease herpes zoster. JAMA. 2011 Jan 12.

305 (2): 160-6. [Medline]. Schmader K, Levin M, Gnann J, McNeil S, Vesikari T, et al. Efficacy, immunogenicity, safety, and tolerability of zoster vaccine (ZV) in subjects 50 to 59 years of age (Poster / Abstract). Infectious Diseases Society of America. The 48th Annual Meeting of the Infectious Diseases Society of America. 10-21-2010. Vancouver, British Columbia, Canada: Ref Type: Abstract: 3363. Pierson DL, SK Mehta, Gilden D, et al. Varicella zoster virus DNA inoculation sites at and in Saliva Zostavax after immunization. J Infect Dis. 2011 Jun 1. 203 (11): 1542-5.

[Medline]. [Full Text]. Galil K, Choo PW, Donahue JG, Platt R. The sequelae of herpes zoster. Arch Intern Med 1997 June 9. 157 (11):. 1209-1213. [Medline]. Rowbotham MC, Fields HL. The relationship of pain, allodynia and thermal sensation in post-herpetic neuralgia. Brain. Apr. 1996 119 (Pt 2): 347-54.

[Medline]. Oaklander AL, Romans K, Horasek S, et al. Unilateral postherpetic neuralgia is Associated With bilateral sensory neuron damage. Ann Neurol. 1998 Nov. 44 (5): 789-95. [Medline]. Baik JS, Kim WC, Heo JH, Zheng HY. Recurrent herpes zoster myelitis. J Korean Med Sci 1997 Aug. 12 (4):. 360-3. [Medline].

JP Carreau, Gola R, Cheynet F, L. Guyot [Zone of the cranial nerves. Current aspects]. Rev Chir Stomatol Maxillofac. 1998 Oct. 99 (3): 155-64. [Medline]. [Guideline] Centers for Disease Control and Prevention (CDC); Advisory Committee on Immunization Practices (ACIP). Update: Recommendations from the Advisory Committee on Immunization Practices (ACIP) Regarding administration of combination MMRV vaccine. MMWR Morb Mortal Wkly Rep 2008 Mar 14 57 (10). 258-60. [Medline]. JI Cohen.

Varicella-zoster virus. The virus. Infect Dis Clin North Am 1996 Sep. 10 (3):. 457-68. [Medline]. JI Cohen, Brunell PA, Straus SE, Krause PR. Recent advances in virus varicella-zoster infection. Ann Intern Med 1999 June 1. 130 (11):. 922-32. [Medline]. Devinsky O, Cho ES, Petito CK, RW Price.

Herpes zoster myelitis. Brain. June 1991 114 (Pt 3):. 1181-1196. [Medline]. Fabian VA, Wood B, P Crowley, Kakulas BA. Herpes zoster brachial plexus neuritis. Neuropathol Clin. 1997 Mar-Apr. 16 (2): 61-4. [Medline]. Feder HM Jr. , La Russa P, Steinberg S, Gershon AA.

Clinical varicella vaccination varicella following: do not be fooled. Pediatrics. 1997 June 99 (6):. 897-9. [Medline]. Gilden DH, Cohrs RJ, R. Mahalingam VZV vasculopathy and postherpetic neuralgia: progress and perspective on antiviral therapy. Neurology. 2005 Jan 11. 64 (1): 21-5. [Medline]. Goh CL, Khoo L. A retrospective study of the clinical presentation and outcome of herpes zoster in a tertiary referral dermatology outpatient clinic.

Int J Dermatol. 1997 Sep. 36 (9): 667-72. [Medline]. Goldman GS. Universal varicella vaccination: efficacy trends and effect on herpes zoster. Int J Toxicol. 2005 Jul-Aug. 24 (4): 205-13. [Medline]. JJ Hong, Elgart ML. Gastrointestinal complications of dermatomal herpes zoster famciclovir and successfully Treated With lactulose. J Am Acad Dermatol.

1998 Feb. 38 (2 Pt 1): 279-80. [Medline]. Hovens MM, Vaessen N, Sijpkens YW, of Fijter JW. Unusual presentation of the central nervous system manifestations of Varicella zoster virus vasculopathy in renal transplant recipients. Transpl Infect Dis. 2007 Sep. 9 (3): 237-40. [Medline]. Liang MG, Heidelberg KA, Jacobson RM, McEvoy MT. Herpes zoster after varicella immunization. J Am Acad Dermatol. May 1998.

38 (5 Pt 1): 761-3. [Medline]. Mainka C, Fuss B, Geiger M, et al. Characterization of viremia at different stages of varicella-zoster virus infection. J Med Virol. 1998 Sep. 56 (1): 91-8. [Medline]. Morgan R, King D. Characteristics of Patients With shingles ADMITTED to district general hospital. Postgrad Med J. 1998 Feb. 74 (868): 101-3.

[Medline]. Nagel MA, Gilden DH. The protean neurologic manifestations of varicella-zoster virus infection. Cleve Clin J Med 2007 July 74 (7):. . 489-94, 496, 498-9 passim. [Medline]. Rowbotham MC, Davies PS, Verkempinck C, Galer BS. Lidocaine patch: double-blind controlled study of a new treatment method for post-herpetic neuralgia. Pain. 1996 Apr. 65 (1): 39-44. [Medline].

L Sparks, Russell C. The new varicella vaccine: efficacy, safety, and administration. J Pediatr Nurs. 1998 Apr. 13 (2): 85-94. [Medline]. GE Stein. Pharmacology of new anti-herpes agents: famciclovir and valacyclovir. J Am Pharm Assoc (Wash). 1997 Mar-Apr. NS37 (2): 157-63. [Medline]. Sugisaki K, Yoshida H.

Varicella zoster virus meningoencephalitis Accompanied by sporadic skin lesions in immunocompetent an older adult. J Infect Chemother. 2007 Aug. 13 (4): 270-2. [Medline]. Svozilkova P, Rihova E, Varicella zoster virus Diblik P. acute retinal necrosis following eye contusion: casereport. J. Virol 2005 Aug 31. 2:77. [Medline]. Vu AQ, Radonich MA, Heald PW. Herpes zoster in seven dermatomes nonsense (zoster multiplex): report of a case and review of the literature.

J Am Acad Dermatol. 1999 May. 40 (5 Pt 2): 868-9. [Medline]. Westenend PJ, Hoppenbrouwers WJ. [Fatal varicella-zoster encephalitis; a rare complication of herpes zoster]. Ned Tijdschr Geneeskd. 1998 Mar 21. 142 (12): 654-7. [Medline]. Galetta KM, Gilden D. Zeroing in on zoster: A tale of many disorders produced by one virus. J Neurol Sci.

2015 Oct. 3. [Medline].

Facial Herpes: Contagion, Symptoms, Treatment and Prevention

 // What is facial herpes? Facial Herpes is very common and is also known as labial fires, fever blisters, orofacial herpes, cold sores and herpes febrilis. Facial Herpes is characterized by a group settle fluid-filled blisters that appear on red swollen areas on the skin or mucous membranes. A burning sensation is often present just before the lesions develop on the skin. The areas can be delicate and painful. Blisters heal without scarring, but they have a tendency to return. These episodes are caused by an infection very common virus known as herpes simplex virus (HSV), of which there are two types: HSV-1, the most common type, which causes genital herpes and facial HSV-2 usually causes genital herpes. Although cross infection can occur, it is more likely to occur face to the genitals (causing genital HSV-1) of the genitals to the facial area. How Facial Herpes Spread?  //

Facial Herpes is spread by direct physical contact with a person infected with the herpes virus and someone who had not been previously infected person. Infection with HSV-1 is most commonly acquired during infancy or childhood as a result of contact with relatives (eg kissing or hugging). The source of infection not always typical facial herpes symptoms at the time of transmission. For example, the herpes virus often emerges from the lips before blisters appear and it is also possible to shed infectious particles of herpes virus without noticeable symptoms. Most people have come into contact with the herpes virus between the ages of three and five years, but only one in three of these will have a first episode of herpes symptoms. What does the virus? HSV invades cells of the epidermis, the outer layer of the skin, causing fluid-filled blisters appear. The herpes virus travels from the epidermis along the nerve pathways to the trigeminal ganglion, a bunch of close to the inner ear, where it is hidden until reactivates nerves. Potential triggers for herpes include fever (eg common cold), UV radiation (exposure to sunlight), extreme tiredness or impaired immune function. The first outbreak of Herpes  // When a person is infected with herpes for the first time, the episode is called a primary infection. Primary infection may progress in different ways.

Some people have only very mild symptoms of herpes or none at all, but others may experience considerable discomfort. The sores can develop inside the mouth, as well as outside it and this is commonly called gingivostomatitis. Initially, this may take the form of painful mouth ulcers affecting the mouth, gums, throat and lips, which can last more than 14 days if untreated. Gingivostomatitis should be treated with antiviral medicine. Most patients also require analgesics or local anesthetics applied directly to relieve the discomfort of canker sores so they can eat and drink. This first outbreak begins one to three weeks after the herpes virus has invaded the skin and subsides within a few weeks. Recurrences Virus The herpes virus remains hidden in the nerves for the rest of the life of the person and becomes active again from time to time. Some people have few or no more herpes outbreaks while others have regular recurrences. These appear to be less frequent with age. An outbreak of facial herpes has four stages: A tingling sensation on the skin. Mild swelling and then the development of a series of fluid-filled blisters, which are often painful.

The blisters burst and form groups, leaving fluid-filled sores (herpes labialis) Canker sores eventually dry, crust over and heal without scarring after 8 to 10 days. The virus can spread until canker sores are completely covered by scabs and infection usually external. Virus Affected Areas  // More commonly, herpes simplex affects the lips or nasal region, causing cold sores. Recurrences can affect the eye region or even involve the eye itself. Ocular HSV infection is also known by several other names, including: herpes keratitis, conjunctivitis and herpes stromal keratitis. A thorough eye infection is very rare, but can cause a syndrome called acute retinal necrosis. In children, the herpes virus can infect the mouth and throat. The infection can be accompanied by fever and general aches and pains. What causes facial herpes? Factors that can trigger herpes outbreaks differ from person to person.

Menstruation, trauma, fever, exposure to sunlight, extreme weather conditions or any condition that affects the immune system, such as a cold, flu or general disease, can cause a recurrence of cold sores in some people. In others, there is a definite cause. Facial Herpes Transmission  // People who experience an episode of herpes, either facial or genital, should be considered infectious from the start of episode of herpes to healing of the last ulcer. During this time the herpes virus can be transmitted to others and, in rare cases, can be transferred to other areas of the body. Increasingly, genital herpes (genital HSV-1) is being caused by contact of the face with an infected person. Remember, most of us acquire facial herpes in the first five years of our lives. To help prevent transmission of herpes, you should avoid: Kissing someone or sharing drinking utensils when you have this lip fire. Oral sex when you or your partner have blisters on the lips or genitals. Sharing towels and hand wipes or mittens. Use saliva to moisten your contact lenses if you have sores around the mouth.

precautions Hygiene is important for people infected with the herpes virus. Try to avoid direct contact with cold sores, but if this occurs, wash hands with soap and water and dry thoroughly. Avoid breathing with cold sores, as it can transmit the virus to other body parts or acquiring a bacterial infection ulcers. Avoid using strong detergents on the skin. The body’s defenses can be strengthened by a healthy lifestyle. Try to eat a varied diet, exercising regularly and getting enough sleep. Using a sunscreen can help prevent a recurrence of cold sores in some cases. How to diagnose facial herpes  // Accurate diagnosis of facial herpes more easily and accurately at the time of an active herpes infection it does. A combination of patient history and the appearance of the sores will usually be sufficient to identify facial herpes. A swab of the lesion or specialized blood test can be used to confirm.

complications Canker sores can become infected by bacteria. If the condition spreads to the eyes, in severe cases, it can damage vision. In patients suffering from atopic dermatitis, in rare cases, herpes labialis may spread to large areas of the body. A massive cold sores can be a sign that another disease, pneumonia or HIV, for example, has weakened the body’s defenses. Treatment Facial herpes can be treated, and sometimes even prevented, with an antiviral drug, acyclovir, which is available in tablet or a cream. Painkillers and a mouthwash to relieve pain may also relieve symptoms. Treatment should be initiated as soon as the first symptoms appear. Each episode of herpes can be treated with tablets or cream to speed the healing process. If episodes are frequent or problematic, taking daily antiviral tablets can help prevent outbreaks.  ]]>

herpes Simplex

herpes Simplex INTRODUCTION Human herpesviruses are grouped into three subfamilies based on differences in viral characteristics (genome structure, cell tropism, cytopathology and latently infected site), as well as the pathogenesis and clinical originated. Human herpesvirus between herpes simplex (HSV) types 1 and 2, varicella-zoster virus (VZV), cytomegalovirus (CMV), human herpesvirus 6 (HVH6) and 7 (HVH7) and Epstein-Bar virus (EBV) are included. The Herpesviridae family is a diverse group of large DNA viruses that share a common morphology group, the basic mode of replication, the ability to establish latent / recurrent infections and the importance of cell-mediated immunity to control infection and cause symptoms. Herpesviruses are large viruses with envelopes, containing double-stranded deoxyribonucleic acid (DNA). The virion is approximately 150 nm in diameter. The cento (core) is surrounded DNA by a capsid containing 162 icosadeltahédrica capsomeres. The capsid is surrounded in turn by an envelope glycoproteins containing. Herpesviruses encode several functions adhesion glycoproteins, fusion and immune escape. The space between the envelope and capsid called tegument and contains proteins and viral enzymes. Like all enveloped viruses, herpesviruses are sensitive to acids, solvents, detergents and desiccation. The herpes simplex virus was first recognized the human herpesvirus.

Herpes name derives from a Greek word meaning meander. The two types of HSV, 1 and 2, share many characteristics including DNA homology, antigenic determinants, tissue tropism, and disease symptoms. However, they can also be distinguished by differences in these properties. The pathogenic mechanisms of HSV-1 and HSV-2 are very similar. Both viruses infect and replicate in cells mucoepiteliales, and then establish latency in neurons innervating local tissue infection. The location of the infection and subsequent disease depends more on the shape of virus invasion. HSV-1 is usually associated with infections above the waist, while HSV-2 usually cause them in the lower half of the body. Other differences between the 2 types include receptor specificity, growth characteristics and antigenicity. HSV-2 is more likely to produce viremia and is associated with systemic flulike symptoms. HSV can cause lytic infection of most cells, persistent infection of lymphocytes and macrophages, and latent infection of neurones. Cytolysis is generally due to virus-induced inhibition of the synthesis of cellular macromolecules, DNA degradation of the host cell membrane permeability, alteration of the cytoskeleton and cell senescence. The virus initiates infection of mucous membranes or penetrates through cracks in the skin. HSV usually causes a localized may be unapparent infection or cause vesicular lesions.

The virus multiplies in the cells of the base of the lesion, and vesicular fluid containing infectious virions. The injury is caused by a combination of viral pathology and immunopathology. Generally it resolves without scarring. The virus spreads to adjacent cells and neurons innervating the area. After infection of the neuron, the nucleocapsid is transported into the cell nucleus and initiates a latent infection. Virus replication can be triggered by various stimuli, and the virus then travels along the nerve in centrifugal direction to cause lesions in the dermatome. Control and resolution of HSV require involvement of humoral and cellular immunity. CASE 2 A two and a half years, the youngest of two older brothers aged 9 and 11 years, has a fever three days of evolution accompanied by restlessness, frequent crying and rejecting food intake resulting from severe pain that causes the appearance oral cavity in a series of some, vesicular and ulcerated others which are also seen on the lips and lip area skin papular lesions. This picture evolved with greater intensity and then decreases approximately 15 days after the beginning heal without leaving a scar. The doctor established clinical diagnosis of the disease, which is caused by viral infection. 1) What is the clinical diagnosis of the disease and how the doctor could set it? Consistent with the above, what would be the etiologic agent?


The clinical diagnosis of the disease is primary herpetic gingivostomatitis. When the clinical picture is typical, the location and morphology of lesions are sufficient to establish the diagnosis. Primary herpetic gingivostomatitis affects children under 4 years, is of sudden onset and symptoms are clear and obvious, gum inflammation occurs, increase volume, bleed easily and are very sensitive because of the ulcerations caused by the multiplication virus. You can also compromise the oral mucosa and tonsils. There is general commitment, fever, weakness and dehydration. secondary bacterial infection occurs by the characteristics of mouth bacteria, aggravating the picture. It has an evolution from 12 to 14 days and in most cases, there are no major complications. Primary herpetic gingivostomatitis is caused mostly in children HSV-1 while young adults can be caused by HSV-1 or HSV-2. In this case the causative agent is herpes simplex virus type 1, alpha subfamily, family Herpesviridae. 2) What laboratory tests can determine the exact etiology of the disease? The diagnosis is established by isolation and identification of the virus. Isolation is the most definitive method for demonstrating HSV infection. a sample of the liquid of the lesion is taken and then inoculated into a cell culture.

HSV cytopathic effects occurs within 1 to 3 days of being inoculated. The cytopathic effect begins with cytoplasmic granulation, after which the cells enlarged and displayed you balonadas. The large cells are rounded and then die. Some isolates induce fusion of neighboring cells, which gives rise to multinucleated giant elements. The demonstration of the presence of multinucleated giant cells and inclusion bodies typical herpetic certifies the nature of the injury. Typing of isolates of HSV can be done by biochemical, biological or immunological techniques. The patterns obtained with restriction endonuclease DNA of HSV-1 and HSV-2 are unique, and allow unambiguous characterization of isolates. It also features antibodies and DNA probes specific for the VHS type, that detect and differentiate between HSV-1 and HSV-2. 3) What is special about this infectious agent in the incidence of clinical disease that causes status and relationship established with any infected host? All human herpesviruses induce a biological state in the host, whereby, after infection, virus permanence established in the infected organism remaining life. In this balance, which can evolve into completely asymptomatic, it is commonly called the “latency”. In the case of primary infection unapparent the virus penetrated the individual, there was no damage or noticeable symptoms, but if there is an immune response with the appearance of a demonstrable level of antibodies. The interesting thing however is that as a result of primary infection (clinical or inapparent) the virus will remain dormant in nerve ganglia of the area in which occurred the protected primary infection antibodies for intracellular character and can be reactivated at any time resulting in recurring pictures, which therefore are of endogenous origin.

These recurrent episodes will always appear in the same place of primary infection (or in its immediate environment) are still present in the presence of a high titer of antibodies and are more localized compared with primary infection, probably due to the action of antibodies that prevent more widespread. Agents that can activate, the latent virus and therefore recurrent disease are varied, including sunlight could mention, ingestion of certain foods, anxiety, hormonal disorders, fever, etc. 4) It is highly likely that his brothers infected with this agent and therefore make the disease or not ? , why? Chances are that if infected, if they are not already infected before, and in the latter case it is also possible that they are infected her younger brother, because in them the disease may have presented asymptomatically. The high possibility of infection is demonstrated by the fact that almost 100% of the adult population has the virus. HSV-1 most often transmitted from an active mucocutaneous lesion, so that it is possible to reduce infection if direct contact is avoided with such injuries. In this case the spread is highly favored by the permanent direct contact with, for example, children can not, also by use of common tools, etc. 5) causes the disease in the child an immune response that comes from life to have any disease caused by viral agent? The immune response that occurs is cellular and humoral. Antibodies against HSV-1 protect against possible future attacks against other strains of the same virus, and to some extent against infection with HSV-2 (and vice versa), but does not confer immunity against other viral diseases. The relative immunity against HSV-2 is probably given by their similarity in DNA, antigenic determinants, cell tropism and pathogenic mechanisms. 6) Are there antiviral drugs to treat the disease?

For a long time the treatment of herpes infections was reduced to symptomatic aspects rather than generic or etiological. it was to lessen the pain hasten the evolution of the vesicles with the use of dehydrating substances and to prevent secondary bacterial infection by applying antiseptics and disinfectants in the case of skin lesions. Herpetic gingivostomatitis cases present more problems for its location and symptoms. In these circumstances local and topical anesthetics are used to reduce pain, antibiotics to fight bacterial infection and in severe cases, administer intravenous fluids to prevent or combat dehydration and acidosis. Most drugs are analogous antiherpetic nucleotides or inhibitors of viral DNA polymerase, an enzyme essential for virus replication and the best target for antiviral therapy. Antiherpes drugs approved by the FDA include acyclovir (ACV), foscarnet (phosphonoformic acid), vidarabine (adenosine arabinoside), idoxuridine (iododeoxyuridine) and trifluridine. Acyclovir is currently the most effective anti-HSV drug. Stroke is activated by viral thymidine kinase and then used as a substrate for viral DNA polymerase. It is incorporated into the viral DNA and prevents elongation. Acyclovir shown effective in the treatment of serious HSV tables for first episodes of genital herpes and as a prophylactic agent. It is indicated in severe HSV syndromes, such as neonatal disease, encephalitis and extensive dissemination in immunocompromised patients. The drug is relatively non-toxic and can be used prophylactically. The most common form of stroke resistance is due to mutations that inactivate thymidine kinase, which reduces the conversion of the drug in its active form.

Fortunately, resistant strains appear to be less virulent. Adenine arabinoside (Ara A) is also approved for the treatment of HSV infection. However, it is less soluble, less powerful and more toxic than ACV.

How to cure a cold sore

Posted on December 19th, 2013 by admin in Herpes, herbs that heal, irritated skin, disease prevention, herbal properties, home remedies, home remedies, natural remedies for skin problems, natural remedies for all alternative treatments oral herpes and using natural remedies to combat it. Oral herpes is caused by a virus called HSV or herpes simplex virus. This virus causes sores inside the mouth. There is a difference between oral herpes, which is caused by HSV-2 and cold sores are caused by HSV1. Cold sores usually appear on the outside of the mouth and can develop on the inside of the cheeks and gums, tongue and palate lips. Herpes is caused by a virus that will always remain in your body. Traditional medicine has not developed a cure for oral herpes, but it can stop or delay outbreaks. How to cure a cold sore is a constant problem for a large percentage of the world’s population. The condition is very contagious when in the blister stage. Cold sores can spread from person to person and in many cases not even know they have it until an outbreak occurs. An outbreak may occur when compromised immune system, you have excess physical or emotional stress, fever, or even hormonal change. How to cure a cold sore?

Strengthen your immune system. Eliminating all junk food from your diet. Changing your eating habits is one of the fastest ways to control herpes outbreaks. You can take antipyretic and analgesic drugs, but it will not help with the outbreak. They might even desguarnecer the body more, so that the outbreak would last longer. It depends on how your body reacts to drugs. Drink plenty of water. Besides salt water rinses help dry the blisters. Some tips to learn how to cure a cold sore How to cure a cold sore 1 – Cover cold sores Covering a cold sore with petroleum jelly will speed healing and help protect it from secondary infection with bacteria. Put an ointment containing benzocaine (local anesthetic) in cold sores can also help relieve pain temporarily. However, the attempt to camouflage a cold sore with makeup, often exacerbates the problem, because the chemicals in makeup can make the pain worse.

Do not share your lipstick or makeup under any circumstances. How to cure a cold sore 2 – Change your toothbrush Get a new toothbrush after the blister has formed. Toothbrushes can harbor the virus. Consult your doctor if blisters of cold sores have severe or frequent. In some cases, you need an antiviral medicine. How to cure a cold sore 3 – Protect your lips from the sun Applying lip sunscreen can help prevent cold sores problems induced by the sun. Look for a sunscreen specially designed for lips that has a good degree of protection. You can also choose a lipstick that contains sunscreen. How to cure a cold sore 4 – lips or affected area Do not touch Do not squeeze, pinch or touch a cold sore. These actions can cause a bacterial infection and cold sores is extremely contagious, avoid kissing and sharing drinking glasses, towels or other items.

Wash your hands often, especially after touching cold sores. Be careful not to touch your eyes or genitals immediately after touching the sore. It’s a good idea to have a hand sanitizer with you in case you accidentally your cold sores from scratching. How to cure a cold sore 5 – Ice packs If you apply ice on the affected area when herpes first appears, it is possible to reduce inflammation. Ice packs and cold compresses provide temporary relief. A tasty ice cream will feel good too, but avoid juices as their acid content can further irritate cold sores. Super- cold drinks, such as iced drinks or shakes, are another tasty way to provide comfort and relief How to cure a cold sore 6 – Milk This remedy does not involve drinking. Soak a cotton ball in milk and apply it to the wound to relieve pain. Better yet, if you feel the tingle witness before the surfaces of cold sores, go directly to the cold milk. It can help speed healing from the beginning.

Excellent carrot and lemon juice to prevent formation of Cold Sores. In the following Ebook “Miracle Herpes” find the best treatment in combating any type of herpes as it is addressed to all persons regardless of sex or age. The proposed treatments are completely natural so you do not run the risk of any side effect and best of all is that the results can begin to be enjoyed in just one week. But it is not bogged down with what I say because you all this and more can check by visiting: Miracle Herpes Here you will find all the information you need to know about this innovative method to combat herpes in a very short time and in a completely natural way. By his life and happiness! Related posts: Treatment of nail fungus Ovarian cysts – Natural Remedies Irritable Bowel Syndrome – Natural Remedies Tagged As: how to cure genital herpes, How to cure a cold sore, cure cold sores, genital herpes, genital herpes home remedies, cold sores, cold sores home remedies, labial herpes, cold sores natural remedies, cold sore treatments

Cold sores, online cosmetics store, Cold Sores of Paulas Choice

Data herpes labialis Despite its name, cold sores are not caused by a cold. However, often they erupt before or during a cold or other illness, when it suppresses or weakens the immune system. Indeed, the cold sore is the result of an infection with a type of virus known as Herpes simplex HSV-1. It is not the same virus that causes genital herpes (known as HSV-2), but they are related. Despite what some believe, cold sores are not canker sores. Canker sores are usually white, puffy and swollen, are injuries that occur inside the mouth. These sores are bacterial infections, viral infections not. Usually they occur after accidentally self inside your mouth and are not contagious bites. You can sorry surprised to find out that according to some medical estimates, 80% of adults are infected with the virus that causes cold sores. However, among this group only 30% will experience outbreaks. That is why, the virus is so widespread, those who have cold sores, have an additional ability to suppress the virus because their immune system produces more antibodies to fight infection. Once you have the virus that causes cold sores, it is forever, because there is no cure.

Even when they appear, the virus hides in the nerve endings in the skin. The virus usually does not migrate, so the lesions tend to occur in the same area at a time, year after year. Undoubtedly, your first injury is the worst. After entering into close contact with someone who has a cold sore, you may be infected. The first outbreak is usually accompanied by fever, swollen lymph nodes and generally unwell. After this first outbreak, the following may appear to have a weakened immune system during a cold or other illness, also can be triggered by stress, extreme temperatures, sunlight (one more reason to apply sunscreen every day) and hormonal changes such as those occurring during menstruation and menopause. Here are some facts to consider about Cold Sores. The typical duration of a cold sore without treatment is 3 weeks. With treatment, most lasting less than a week. Most of those who have cold sores suffer two to three outbreaks per year. It’s a good idea to always keep a source of oral or topical medication list (even when you are traveling). Cold sores can be triggered by a variety of factors, as mentioned above and also by excessive alcohol consumption, pregnancy and steroid medication (such as those for asthma). What looks like a cold sore?

The classic Cold Sores resemble a cluster of raised red blisters. In fact, another name for cold sores is “feverish” because, like other health problems that suppress the immune system, have high fever can cause an outbreak in people with HSV-1 virus. The herpes usually appear around the mouth, often on the border line between the lip and the skin around the lips. The range of diameter size of blisters are the size of the diameter of a pencil eraser or a small coin. Although cold sores are seen more often around the mouth, it can also appear on the cheeks, chin or nose. Cold sores rarely appears in other parts of the body. Regardless of where you look, cold sores is usually filled with a clear liquid, which eventually oozes out and then dried, forming a crust like a crust over the sore. Crust area may be greater than cold itself. Before look observe herpes, often you feel a tingling, itching or burning in the area, where it is about to appear. This can happen a few hours or a few days before the fever rears its ugly head. This is the time to start topical medication; doing so can prevent the eruption of herpes and shorten healing time. Treatment of cold sores Although cold sores are a nuisance and can not cure the virus that causes it, there are several treatment options to control the infection, reduce discomfort and speed healing time.

Most herpes, better respond to treatment or oral prescription topical (some cases require both at the same time), but there are alternatives without a prescription, too. Oral medications used to treat cold sores are Zovirax (acyclovir), Famvir (famciclovir) and Valtrex (valacyclovir). They all work to stop the replication of the virus in the early days of an outbreak. By reducing viral replication, the immune system of the skin is an opportunity to handle the infection, virus causing the return to its dormant state (inactive). Follow the dosage instructions of your doctor for these medicines and note that the active ingredient in Zovirax (acylclovir) is available for topical use, too. Among the topical medications prescribed to treat cold sores, Denavir (penciclovir) cream is considered the best. This medicine speeds healing, helps minimize viral shedding (making it less infectious) and reduces pain. For best results, apply the product to the first sign that observe and if it appears should apply throughout the day (at least every 2 hours while awake) treatment for 4 days. Abreva (docosanol) is the main option without prescription topical to treat cold sores. It must be used at the first sign of a cold sore and applied at least 5 times a day until the cold sore has faded. Although abreva generally is not as effective as prescription options, worth a try and is significantly less expensive. You may have heard that topical application of lemon balm, rhubarb with Salvia and oil tea tree, help treat cold sores, but there is little convincing research results and do not work better (or faster) than options standard recipe. Most of these can cause irritation, worsening the appearance of herpes and may even delay the healing.

Along with prescription or OTC medications, there are some additional tips for the treatment of cold sores: With any treatment of cold sores, you should apply an antibiotic ointment on the area as Polysporin. This helps prevent the wound becoming infected with bacteria normally found on the skin. Secondary bacterial infection may be created when the fever blister breaks, leaving the area vulnerable skin. Apply the ointment after applying the medication for cold sores. Those with chronic herpes (more than one outbreak every 2 or 3 months) should be considered a low-dose regimen of antiviral drugs to minimize or potentially eliminate outbreaks. Your doctor will advise you on the possibilities. The amino acid L-Lysine is a popular natural remedy for cold sores, but there is little research on their effectiveness demostranda, this principle is not harmful, so you can test it to see if it helps you. L-lysine is also available for topical use. Use a lipstick or lip balm with sun protection religiously, even when the injury is not present, but for hygienic reasons, once your skin has healed, you should replace any lip balm that you used on an active cold sores. Precautions on cold sores you should know There is some confusion about when and for how long are contagious injuries and what steps you should take during an outbreak. Follow the guidelines listed below and you can avoid injuries spread or worsen existing infection:

Lip herpres not spread when they are not visible, because the virus that causes cold sores, does not shed viral particles unless there is a blister. If an outbreak of herpes is not visible, it is not contagious. Avoid skin contact with skin (kissing) when cold sores visible or is healing; the virus can be transmitted in this way and during this time. A cold sores should be completely healed so it is not contagious. No drinking glasses, straws, utensils, toothbrushes or products for lip care until the wound is completely healed. Always lávete hands after touching a cold sore. It is possible to spread the virus to other parts of your body if you stay in the fingertips. For example, rubbing your eyes after touching a cold sore, you can transfer the virus particles to this area and can cause serious problems. Avoid touching cold sores scabs! We know it is difficult, but can increase the risk of scarring and potentially spread to other areas viral particles, generating other herpes. If the crust becomes uncomfortably dry or itchy, apply a thin layer of antibiotic ointment or apply warm compresses. Using makeup to hide a cold sore When a cold sore appears, as you probably want to hide.

Due to the delicate texture and eventually crust of cold sores, is easier said than done, but it is possible! The trick is to use a light concealer on the skin and provides good coverage, with only apply a small amount of product. Here are the steps to hide a cold sore, but remember: if you use makeup to cover a cold sore, you’re going to make more obvious the injury, so it is preferable to avoid make up, be patient and let it heal: Make sure the skin around the wound is clean and dry; you may need to apply a thin layer of moisturizer or rub the area with a soothing tonic, but be careful not to break the crust of cold sores. With a brush, apply a thin layer of liquid or corrective cold sores and skin cream surrounding. Apply it with a soft dotted movement (circular motion, gently pat) and repeated until the desired coverage is achieved. You can use our Soft Cream Concealer. Use the tips of clean fingers or a makeup sponge to spread the mixture on the edges. With this you consiguiras, you avoid the crust itself why any pressure can break the lesion. You can apply very lightly Set loose or compact powders with sunscreen, but not much quantity as resecarás the wound. Check the results to natural light, to make sure the area does not look caked or too dry, which called more attention than they intend to hide. When painful and unsightly scabs appear, we understand that you have every reason to wish them away as soon as possible. Following these steps and experimenting to find what works best for you, you can treat the problem as effectively as you possibly can, so you can cross an outbreak with minimal discomfort and prevent the spread of infection to others.

Cold Sores: 10 Natural Remedies

Cold Sores: 10 Natural Remedies http://www. ellahoy. es/salud/articulo/herpes-labial-10-remedios-naturales/210585/ Wounds in the mouth are often a nuisance, as in the case of herpes, can last several days and even accompanied by fever. How do you kill them? Discover the best natural remedies.  Cold sores are caused by an infection (HSV 1, herpes simplex virus) virus and generally usually appears between the lip mucosa and skin that surrounds them. Herpes must be treated, not only because it is contagious but that may be accompanied by other symptoms such as fever, malaise, itching, swelling, blistering and even swollen glands. In addition to the invisible patches or antiviral ointments, we can also use natural remedies to accelerate healing. 1. Tea Bags  Among the many therapeutic properties of tea it is also included to help reduce cold sores, thanks to its content in tannic acid which prevent the injury from spreading.


The herpes virus can be very persistent, you can even become dormant in the nervous system and reactivated to a lowering of defenses. 2. Lemon juice  The acidity of lemon juice stimulates crusting, helping the lip area affected by the appearance of herpes labialis regenerate without scarring. It can be applied directly to the affected area, using a tissue or cotton swab dipped in lemon juice. 3. Extract horsetail  Among the natural remedies that we can use to accelerate the healing of herpes extract horsetail, a particularly valuable plant for skin care because it contains sulfur, calcium, zinc and organic silicon, a substance that helps it is included to restore the balance of damaged cells. 4. Essential oils  Among the essential oils that can help alleviate the annoying symptoms (itching, burning or swelling) of herpes labialis the tea tree oil, which can be taken orally is included, always consulting the doctor. Meanwhile, plant oils such as eucalyptus or geranium are effective for topical use. 5.

Honey  The nectar of bees has many therapeutic properties, and one of them is their ability to alleviate the symptoms of cold sores and can be used even during pregnancy. Honey, good for the skin, helps speed healing and crusting, without any side effects. 6. Ice  A basic, simple and always at hand remedy ice. When the blisters begin to appear characteristics of cold sores, we can apply some ice cubes (wrapped in a handkerchief or towel) directly on the affected area to slow down its development and alleviate the annoying symptoms that can produce area. 7. Legumes and soybeans  A healthy diet is also a natural remedy for herpes. In fact, its appearance is associated with episodes of stress, nervous tension and lowering of defenses. To speed healing may be useful to include in the diet lysine, a substance that regenerates tissues and can be found in legumes and soybeans. 8.

Foods to avoid  Just as we must review the diet to include some beneficial foods, there are some foods that should be avoided at the onset of a cold sore, because their properties may reactivate the virus remains dormant in the nervous waiting System reappear . Is coffee, soft drinks or chocolate. 9. Toothpaste  One of the remedies grandmother against cold sores is toothpaste, which is applied directly to the area affected by the blisters lips. Simply apply a thin layer of pasta, must leave it overnight, to heal faster. 10. Vinegar  Another remedy is vinegar white wine, whose properties help speed healing of herpes. It is applied to the area a cotton swab dipped in vinegar and then dry lips. Not just Herpes appears to be infected, it can take between one and three weeks.

QUESTIONS AND ANSWERS – IBC DEBOREM

1 – What is herpes? It is an infectious, contagious, widespread disease caused by a virus called Herpes Simplex Virus (HSV), of which there are two species (HSV-1) and herpes labialis (HSV-2) herpes. This virus appears periodically in outbreaks of herpes called “repetition”. 2 – What are the symptoms? At the beginning of a painful kind feeling of warmth, cooking, itching, redness, followed a few hours later vesicles isolated button (1-48 hours) or grouped (transparent blisters) filled with a clear liquid and disorder, which break leaving ulcers and scabs to wound healing. Relapses or recurrences last 2 to 15 days. The sensation of pain is generally stronger in women. 3 – How the herpes virus infects us to you? This is always a contact contamination. When pimples or blisters appear, which can free viral cells that migrate through the skin and infect another person simply contact. The virus attack or is internally usual skin protection is therefore no defense during the initial development phase of herpes button. After the appearance of vesicles, then superinfection can occur at any time. Skin weakened at this point may leave other types of infections (Staphylococcus etc.

). 4 – How is herpes? The herpes virus is by direct contact on the skin or mucosa of a host. It penetrates the epidermis to the dermis or rapidementà hangs a nerve cell. He will be able to manufacture tens viral cell in the completion of the nervous system infected, can infect a new host or Auto-contaminated by casual contact. It will never happen in the bloodstream, it will pass only through the nervous system that is independent infected. Your immune system never find it and not be able to destroy because it is part of the nerve cell infected Adn equivalent. When it moves to double its base (node) to nerve endings in the epidermis is the active phase virus, which lasts from 2-24 hours, then it returned in the lag phase for a long time (inactive). for this time, viral cells in duplicate pustules pass through the skin or injury If scratched. It can be contagious for several days until complete resorption pimples or pustules and crust disappears, sometimes up to 15 days. 5 – What are the precautions? To avoid superinfection: – Do not touch the infected or immediately wash your hands with disinfectant soap.

– Avoid scratching the area especially when the blisters begin to form, finding the virus spread is facilitated. – Avoid contact with eyes virus (ocular herpes can). – Never put steroids on herpes. They promote proliferation and viral pathogens allows to move into the wound. – Never place of pure alcohol or undiluted essential oils. 6 – What is the vesicles? This name comes from Latin and literally means “small bladder”. It is an inflammatory compound of small buttons or pockets transparent reaction. The vesicles are often associated with genital herpes and instead is in intimate areas. However, you can also find them in all areas of the body other than the head (herpes labialis). This inflammatory process is divided into 4 phases: • Phase vascular redness, heat, pain, swelling. • The phase cellular reaction: tissue vasodilation.

• The tissue cleaning phase: Effect of increasing local pressure and permeability of the vessel wall. • The tissue healing. 7 – is the herpes considered a serious disease? No, this is a benign disease, but some very rare cases may be serious or even problematic (ocular, visceral or brain herpes, people with immunodeficiency). This disease has repercussions mainly disturbance of sex life and the psychological intimacy of those affected. A herpes lesion weakened areas of mucous membranes or skin and increase the risk of acquiring or transmitting any other Sexually Transmitted Infections (STI) infection. 8 – How to diagnose herpes? You should consult your family doctor or dermatologist for diagnosis by prescribing the necessary analyzes. 9 – How long does a herpes outbreak? Between 3 days and 3 weeks (even longer for cases of herpetic neuralgia) 10 – Can you get herpes through blood transfusion? No, you can not get herpes from a blood transfusion. The herpes virus is not present in the blood.


If that were the case would be immediately destroyed by the immune system. 11 – Is oncogene herpes virus? I do not. 12 – For there is infection, you should touch the blisters and then another part of the body. That’s right? If I am. 13 – Having type 2 herpes avoider you have type 1 herpes? Infection with one virus does not protect against infection by the other. 14 – Have yourself a cold sore that immunizes against herpes labialis spouse? Not at all, you can create one or more outbreaks. 15 – Antiviral cure herpes? No, its function is to weaken viral load and thereby reduce duplication of the virus, but do not allow not to get rid of recurrences. Antiviral not involved in virus penetration into cells, do not prevent the initial tissue destruction because the antiviral affects viral replication wherein the site is contaminated core cells.

To get to the essence, the virus must meet a series of steps, the first is the penetration into the cells were targeted. However, once the virus is capable of crossing the membrane separating the cytoplasm immediately whole cellular machinery is diverted for exclusive benefit and is at this stage that the tissue damage resulting in the formation of vesicles begins. 16 – Can we go to the pool with an outbreak of herpes? Yes, the virus is not resistant to conventional treatments pool chlorine or bromide, or salt, is a virulent virus but very fragile outside an organization. 17 – Speaker, we must prevent your gynecologist if we had a single outbreak of herpes in his youth? Yes, in all cases you must notify your gynecologist. 18 – Herpes is transmitted only by pollution or also by genes, heredity? Not only by pollution. 19 – It can transmit oral herpes to a baby diaper changing? Yes, frequent hand washing with disinfectant soap and protect his injury during a push to prevent accidental touch your wounds. 20 – Sucked done with a cold sore is risky for the couple? Yes, significant risk of transmission. 21 – Is it possible to get genital herpes by friction in a toilet?

Through urine, without risk, contact immediately after contamination of the cup, yes, it is likely. 22 – Are the sores of herpes? No, absolutely not. 23 – Is there a link between cold sores and fibromyalgia? Any. 24 – Is there a link between cold sores and multiple sclerosis? Any. 25 – The insensitivity of the lips affected by herpes is irreversible? No, cure or disappear after some time without damage. 26 – genital herpes can be in the anal area? Yes, all areas of the body below the head may be affected by genital herpes, for the head, you can change the area and become “cold”. 27 – Can a tingling and burning of the lip to be a push no signs cold sores (herpes labialis)?

Yes, especially if it is regularly in the same place, there is not necessarily pustules, it just means that the virus is rather low. Evolution is random. 28 – A-ti one less attack of herpes greater? No, seizures occur only during an immune or nervous weakness, regardless of age. 29 – certain materials underwear pants are too tight or can promote outbreak of genital herpes? I do not. 30 – Can a herpes outbreak have an allergic cause? No, but allergies can trigger an outbreak of herpes decrease immunity. 31 – Can you sleep without underwear in case of genital herpes? Avoid during crises, it is better to sleep with your underwear to avoid self-contamination, wash hands regularly and avoid touching the lesions . . . 32 – I have herpes in the lower back and buttocks.

What type of herpes is? This is the type of herpes 2, a very common form. 33 – Can I drill a cold sore when it first appeared? No, this is to avoid the risk of inoculation would be more important elsewhere. 34 – Type 1 herpes may be in other body parts such as fingers? Yes, but in a milder form, the exchange area virus type 1 with ease, but does not migrate, is a new HIV infections a new area. 35 – Should we intervene immediately or is it better to do nothing and wait it out? Treatment should be used as soon as possible. Once the feeling or doubt about a push. 36 – Herpes he still has the form of cold sores? If not what would? No, sometimes a simple redness, sometimes burning sensation without vesicles. 37 – What are the risks of a newborn if the transmission during childbirth?

The risk of neonatal herpes 1 in 10,000 newborns (herpes encephalitis or generalized) 38 – can be contaminated with a lipstick or a cream of protection that have been in contact with a cold sore? Yes, there is a risk if the infected person comes to use (within a medium / previous hour) 39 – Can I become infected by drinking from the same glass or bottle used by someone with a cold sore? Yes, if the contact is recent. 40 – How an ocular herpes is obtained and how do you get? By direct contamination, usually by fingers

Herpetic esophagitis in the immunosuppressed child

Bol Med Hosp Infant Mex 2004; Vol 61 (1):. 29-34 ORIGINAL ARTICLE Herpetic esophagitis in the immunosuppressed child Dr. Gerardo Blanco Rodríguez Service of Thoracic Surgery and Endoscopy, Hospital Infantil de Mexico, Mexico D. F. , Mexico. Dra. Yolanda Peña Alonso Rocio Pathology Department, Hospital Infantil de Mexico, Mexico D. F.

, Mexico. Dr. Jaime Penchyna Grub Dr. Adrian Ponce Trujillo Dr. Espinosa Placido Rosas Dr. Jorge Rivas Madriñán Service of Thoracic Surgery and Endoscopy, Hospital Infantil de Mexico, Mexico D. F. , Mexico. Request for reprints: Dr.

Gerardo Blanco Rodriguez, Service Thoracic Surgery and Endoscopy, Hospital Infantil de Mexico Federico Gomez, Dr. Marquez # 162, Col. Doctores, Deleg. Cuauhtémoc, CP 06720, Mexico, DF, Mexico. Date Received: 17/07/2003 Approval date: 30-10-2003. SUMMARY Introduction. Herpes esophagitis is a disease that occurs mainly in immunosuppressed patients; until 1985 most cases were diagnosed during autopsies, what has changed with the advent of endoscopy. Material and methods. records of immunosuppressed patients who were asked endoscopy and biopsies January 1992 to June 2002 were reviewed, analyzed: age, sex, symptoms, oral lesions, endoscopic and histological findings and underlying disease. Results. 137 cases were analyzed, of which 12 had esophagitis herpes virus group, 6 were female and 6 male; age ranged from 14 months to 15 years.

Five patients had leukemia, 5 had any solid tumor, Kawasaki disease 1 and 1 Kidney transplant. The main symptoms were dysphagia and drooling. Ten patients had lesions in the oral mucosa and endoscopy showed ulcers and white patches. Histological studies in these cases showed characteristic changes of herpes virus infection. Conclusion. Twelve immunosuppressed patients with esophageal symptoms had esophagitis herpes virus. The most constant symptoms were dysphagia and drooling. Endoscopy locates lesions and by taking biopsies reach the etiologic diagnosis and indicate the management to follow. KEYWORDS. Herpetic esophagitis; endoscopy; biopsy. ABSTRACT Introduction. Herpetic esophagitis is mainly in immunocompromised Patients Observed; Were before 1985 most cases diagnosed at autopsy but has changed esta With the introduction of endoscopy.

Material and methods. Clinical charts of immunocompromised Patients (n = 137) in Which an endoscopic procedure was practiced, from January 1992 to June 2002 Were reviewed period; age, gender, symptoms, oral lesions, main disease, endoscopic histopathological findings, Were reviewed. Results. Herpetic esophagitis was found in 12 of 137 cases, 6 Were females; age varied from 14 months to 15 years; main disease was leukemia in 5 cases, a solid in 5 tumor, Kawasaki’s disease in 1, and renal transplant in 1. Main symptoms Were Observed dysphagia and syalorrhea; In 10 cases oral lesions Were present. Esophageal ulceration and white plaques Were Observed in the endoscopic study and the characteristic of Herpes virus infection Changes Were Observed in the histopathological study. Conclusion. We present 12 cases of herpetic esophagitis in immunocompromised children in Whom syalorrhea and dysphagia Were the main symptoms. KEY WORDS. Herpetic esophagitis; immunocompromised children. Introduction There are different microorganisms capable of damaging the esophageal mucosa in the immunosuppressed patient, these Candida ranks first, followed by herpes virus. fifteen

Herpetic esophagitis is a disease that occurs primarily in immunocompromised 1,2,6-8 but has also been reported in patients immunocompetent children. 4,6,9,10 In most reports prior to 1985 diagnosis of this entity was made by autopsy, causing 5. 7 to 25% of esophageal ulcers. Endoscopy has established the diagnosis in early stages, allowing timely treat the sick and avoid complications that endanger life. Although there are approximately 70 types of herpes virus in nature, only Herpes simplex types I and II, Herpes zoster, Epstein Barr virus, Cytomegalovirus Herpes VIII and cause infection in humans. 2. 7 From the above, Herpes simplex I, Herpes zoster and may cause ulcerative esophagitis. 3. 5 Because the injuries caused by these viruses are morphologically indistinguishable, it is necessary to consider other clinical features such as the presence of skin lesions. 7 It has reported an increase in the frequency of herpes virus esophagitis 1. 2 in immunocompromised patients with cancer or who have been transplanted; found as predisposing factors in these cases the use of chemotherapy and radiotherapy 1-3. 5 steroids.

3. 5 the frequency of this complication occurs in patients of this hospital, what are the most common symptoms and endoscopic findings it is unknown. So the aim of this study was to establish the frequency of herpetic esophagitis and clinical characteristics of immunosuppressed patients merited endoscopy and biopsy at a pediatric tertiary hospital care. Material and methods Records of immunocompromised patients who underwent endoscopy and biopsy January 1992 to June 2002 and were selected who underwent histopathological diagnosis of herpetic esophagitis were reviewed. We analyzed: sex, age, symptoms, presence of lesions in the oral cavity or skin, endoscopic findings, histopathological changes, underlying disease and the relationship of the lesion with the last cycle of chemotherapy or steroids. For the endoscopic procedure, all patients were placed peripheral venous access, were monitored with electrocardiograph and pulse oximeter, carrying out examination of the oral cavity, balanced general anesthesia with endotracheal intubation was administered, it was performed panendoscopy with endoscope Olympus brand 7. 8 mm in children under one year or under 10 kg weight and 9. 8 mm Pentax videopanendoscopio older; esophagus, stomach and duodenum was revised, taking biopsies of lesions, which were placed in formalin eosin and sent to the Pathology Department, where they were set eight to ten hours, embedded in paraffin, making cuts 4 μ of thick hematoxylin and eosin staining. Histopathological diagnosis of herpetic esophagitis was established when there was ulceration or erosion of the esophageal epithelium and epithelial disruption adjacent characterized by globose degeneration of epithelial cells, with small intranuclear type Cowdry A eosinophilic inclusions or inclusions covering the entire core, Cowdry type B besides multinucleated cells. 4 results A total of 137 records of immunosuppressed, studied 82 patients were male (59.

8%) and 55 female (40. 2%). Of these, only 12 (8. 8%) was documented herpes virus in histopathology, of which six were male and six female; by age group were found, two infants, three preschool, four school and three teenagers. The underlying disease was leukemia in five cases, three osteosarcoma, one with Wilm’s tumor, one with Hodgkin’s disease, one with Kawasaki disease and a kidney transplant for chronic renal failure. Ten patients had received prior chemotherapy; patients with Kawasaki and the transplanted were taking steroids. Clinical symptoms were dysphagia in eight, six drooling, vomiting in two, gastrointestinal bleeding in two, one had asthenia, weakness, cough, fever, shortness of breath and headache, abdominal pain in another. The findings in the oropharynx mucosa were: ulcers in four cases, three white plaques, ulcers with two white plaques, congestion and edema of the gums in one, without the presence of injury two. None of the patients had skin lesions. As for the medical management, six cases received no prior treatment, two antibiotic, antiviral and antifungal, one antibiotic and antiviral, other gamma globulin, antibiotic and antiviral, antifungal and two only. Endoscopic findings were: Seven patients with ulcers in lower third (one confluent), three with white plaques, which were small, medium or large, two ulcers and plates (Fig. 1), two further mucosa hyperemic and friable in one mucosal bleeding and mucosal purplish one aspect. Histological sections of all biopsies showed mucosal ulceration in most cases.

In the bed of the ulcer had mixed inflammatory infiltrate; epithelial cells adjacent to the ulcer showed abundant cytoplasm, sometimes hyaline aspect, vesicular nuclei and eosinophilic inclusions small, Cowdry type A, and intranuclear inclusions displacement homogeneous chromatin towards the nuclear membrane (Cowdry type B); in seven cases they were identified multinucleated cells with nuclei “bag of marbles” which sometimes were in the shed from the mucosa (Figs. 2 to 4) epithelium. Three cases also showed bacterial colonization and two fungi. One of the patients had lesions in the oral mucosa was made a scraping showed multinucleated cells with homogeneous intranuclear inclusions. Discussion , Although rare, esophageal herpes virus infection is seen most frequently in the immunocompromised patient. Most series have been reported in adults and as necropsy findings, and few cases of children with this disease. For the diagnosis of herpes esophagitis caused by endoscopy plays a key role, not only because it allows the visualization of lesions but also perform brushing or biopsy. In this series there was no gender predominance. He appeared in all age groups from infants. All patients had a disease or predisposing medical treatment; in 83. 3% it was due to a neoplastic disease; 83. 3% had a history of having received prior chemotherapy; while two (16.

7%) steroid use was documented. Of neoplastic diseases, leukemia had half and half solid tumors. What differs with McBane and Gross, 1 reported that a third of his cases had a hematologic disease (7 of 23 patients), followed by solid tumors in chemotherapy or radiotherapy (4 of 23), immunosuppression for rheumatoid diseases (6 23), and in 2 of 23 kidney transplant; only one a predisposing factor was found. While Agha et al. 2 reported immunosuppression in the 12 patients in their series, three with histiocytosis, two with leukemia, three diabetes, steroid use two, one with burns, two kidney transplants, one with carcinomatosis and one HIV +. Nash and Ross 4 reported in their study of 14 autopsies of adults, as a predisposing factor, malignant neoplasms in four (leukemia, lymphoma, breast cancer, lung cancer), renal transplantation in three, major surgery of aorta in two, burns two, aplastic anemia, brain abscess, and viral myocarditis in one of each. Levine et al. 8 reported a predisposing factor in six patients (malignancy or immunosuppressive therapy). In studies it is reported that symptoms vary from asymptomatic patients, even dysphagia, sore throat, chest pain and gastrointestinal bleeding. In this study 1,2,4,7,8,11 symptoms were present in all cases. It predominating dysphagia (66. 7%), followed by salivation (50%), vomiting (16. 7%), bleeding (16.

7%), general (8. 3%) symptoms, unlike what was reported by McBane and Gross 1 no pain found chest as a symptom, reported in his study dysphagia in 52%, nausea or vomiting in 39%, fever in 35% and bleeding in 34%. Agha et al. 2 reported prevalence odynophagia (10 of 12) and bleeding (3 of 12). Lightdale et al. 5 dysphagia and chest pain observed in 100% of patients. Levine et al. 8 reported in four of six patients and two sore throat gastrointestinal bleeding. oropharyngeal lesions were found in 83. 3% of patients: isolated in 33. 3%, ulcers with whitish plaques in 16. 7%, 25% white plaques, ulcers Gingivostomatitis 8. 3%; without injuries oropharynx 16.

7%. While Lightdale et al. 5 and Levine et al. 8 they found only in 50% of cases and Gross McBane and only 1 in 20%. Endoscopic findings reported include: inflammation 1 vesicles, ulcers 1-3,5,7-9 1 to 3. 8 resizable and typically shaped volcano, 2 more common in lower third, 5,7,9 and pseudomembranes , 1,2,8,9 of which the only typical herpes lesion vesicles are. 3 In this study found no blisters, ulcers finding 75%, of which 90% were in the lower third and 10% in the middle third; of these, 16. 7% were accompanied by white plaques. Being in only 25% white plaques. In addition ulcer patients was found in two hyperemic and friable esophageal mucosa, the purple one and another esophageal mucosa, esophageal bleeding. The findings regarding the ulcer are similar to those of McBane and Gross, one who was found in 17 of 23 patients (73. 91%), pseudomembranes in 5 of 23 patients (21. 74%); while Levine and col.

8 found in his series of six to three patients with ulcers: two plates and one with ulcers and plaques; and Lightdale et al. 5 refer ulcers and erosions in two of four patients two. Agha et al. 2 endoscopy performed eight of his 12 patients, finding in all esophagitis predominantly in distal third, and in six ulcers, and exudates in the eight; the location is similar to that found in this study with presence of ulcers distal eight of nine patients. It can be concluded that although the ulcer is an injury that should suggest herpes esophagitis is not pathognomonic of this disease, so the biopsy and / or brushing is necessary to reach the correct diagnosis. In contrast esophagram 2,7,8 ulcers can be observed and plates; 2, 8 in this study patients was performed by endoscopy accessibility, this being more specific for lesions of the esophageal mucosa and for biopsy or brushing. The diagnosis is established by histopathologic or brushing study by culture or biopsy. 1 to 4. 8 In all patients in this study the diagnosis was established by biopsy. Morphological changes of herpetic esophagitis are characteristic and it is interesting that in this study, the inflammatory infiltrate was mixed bed of ulcer, unlike what has been observed in other studies. 4,12 is sometimes difficult to establish the diagnosis because the biopsy does not always include the adjacent epithelium in these cases may be useful to some of the more specific techniques such as immunoperoxidase staining or in situ hybridization, using an oligonucleotide probe specific for herpes simplex type I, which is employed in tissue sections included in parafina. 13 Whenever possible, it is recommended to send a fraction of the culture sample, since the sensitivity of the crop is higher than the cytological or histological study. 1

The loss of integrity of the epithelial barrier may be the gateway to other microorganisms, so herpetic esophagitis may be associated with bacteria or fungi, as observed in five cases: three showed colonization by bacteria and two fungi. Gross McBane and one report associated in 23 patients, ten bacterial infection, fungal nine, cytomegalovirus, Pneumocystis carinii in three and two. They have been reported complications caused by herpes simplex, such as bleeding, esophageal perforation, fistula and visceral dissemination, 2 finding only bleeding in one case and spread to the stomach and duodenum in two cases. Nash and Ross 4 reported herpes infection in other organs in six of his 14 autopsies; no such complications were found in cases of this study. REFERENCES 1. McBane RD, JB Gross. Herpes esophagitis: clinical syndrome, endoscopic appearance, and in 23 Patients diagnosis. Gastroint Endosc 1991; 37: 600-3. [Links] 2. Agha CF, Lee HH, Nostrant TT. Herpetic esophagitis: a diagnostic challenge in immunocompromissed Patients.

Am J Gastroenterol 1986; 81: 246-53. [Links] 3. Kadakia SC. Viral esophagitis: the endoscopic appearance. Gastroint Endosc 1992; 38: 633-4. [Links] 4. Nash G, Ross JS. Herpetic esophagitis: a common cause of esophageal ulceration. Hum Pathol 1974; 5: 339-45. [Links] 5.

Lightdale CJ, Wolf DJ, Marcucci RA, Salyer WR. Herpetic esophagitis in patient with Cancer: ante mortem diagnosis by cytology brush. Cancer 1977; 39: 223-6. [Links] 6. Rolston KV. Upper gastrointestinal disease in human immunodeficiency virus-infected Individuals. Arch Intern Med 1992; 152: 881-2. [Links] 7. Weiden PL, MD Schuffler. Herpes esophagitis complicating Hodgkin’s disease. Cancer 1974; 33: 1100-2.

[Links] 8. Levine MS, Laufer I, Kressel HY, HM Friedman. Herpes esophagitis. Am J Roentgenol 1981; 136: 863-6. [Links] 9. Ashenburg C, Rothstein FC, Dahams BB. Herpes esophagitis in the immunocompetent child. J Pediatr 1986; 108: 584-7. [Links] 10. Bastian JF, Kaufman IA.

Herpes simplex esophagitis in a healthy 10 year old boy. J Pediatr 1982; 100: 426-7. [Links] 11. Corey L, Spear PG. With viruses herpes simplex infections. N Engl J Med 1986; 314: 749-57. [Links] 12. Greenson JK, Beschorner WE, Boinott JK, JH Yardley. Prominent mononuclear cell infiltrate is characteristic of herpes esophagitis. Human Pathol 1991; 22: 541-9. [Links]

13. Bruner JM. Oligonuclotide probe for Herpes virus: use in paraffin sections. Mod Pathol 1990; 3: 635-8. [Links]

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VIRUS HPV Human Papillomavirus HPV cure Tem e sua na Boca Relao com or Oral Sex Ol tudo bem Eu sou o Dr Marcelo e neste ns video we falar on or HPV or Human Papilloma VRU or HPV to doena sexual transmisso mais comum between as sexually doenas transmissveis caused human papilomavrus hair existem mais 100 types of HPV that podem infect as genitais areas and tambm ea mouth throat more to maioria two types of non preliminary hpv for pessoas as a maioria das pessoas com hpv that infected so that no sabem so you mesmos carriers ð This doena types of HPV genital area infectam podem. Infect tambm of mouth and throat or HPV mouth and throat is na conhecido as oral HPV. Alguns types of oral hpv conhecidos type high ridge podem causarleses cancerizveis nas areas of cabea or pescoo outros do types mesmo VRU conhecidos rates baixo risco podem cause na warts mouth ou na throat, na maioria two cases to infeco hair hpv all desaparecem types before you possam cause problems Quais sade types of cancer of cabea and pescoo podem cause or HPV cause cancer or HPV prune back na da na freqentemente mais throat base gives. Lngua and tonsils numa conhecida as oropharyngeal area. Essas leses so chamados of malignant oropharyngeal cancer. Quais so you sinais and symptoms do cancer of the oropharynx Os sinais and symptoms podem include persistent feridas na throat dor ouvido, rouquido, lymph glnglios inchados, dor year then swallow and perda unexplained weight algumas pessoas podem not apresentar sinais ou symptoms Quo Common or HPV oral Americans Estudos da populao revelaram than 7 tm oral HPV But only 1 tem or oral HPV type found oropharyngeal cancer em HPV type 16 or HPV oral quase vezes mais comum em homens trs. Do mulheres em. Estudos sugerem than or HPV pode be transmitted during or oral sex ou at mesmo atravs of beijos, esse type of transmisso not muito frequente devido s substncias protetoras gives saliva reduzir posso meu crag to transmit ou acquire HPV oral or condom use since used and corretamente constantly prune reduzir or crag contrair or oral hpv because agem as uma barreira and podem stop propagao do VRU of pessoa pessoa for more as areas not protected condom hair podero this cause. Transmisso do VRU There um test to check is sou carrier do HPV oral Check com seu dentist about to necessidade to perform bipsias is voc tiver algum type of lese before qualquer symptom that possa appear early sinais of cancer of Qual oropharynx or tratamento for or HPV oral or tratamento mais indicated for this type of lese na oral cavidade, to cirrgica remoo dessas leses. Podem Vacinas against or prevent or hpv hpv oral and oropharyngeal cancer or HPV atualmente Vacinas against non-market disponveis foram desenvolvidas to prevent or cancer of. Tero Colo em outros cnceres genitais less Communes possvel that Vacinas as HPV possam tambm prevent or oropharyngeal cancer, pois previnem to initial infeco two types of HPV that cause cancer of the oropharynx podem. recentes Estudos made na Costa Rica comprovam to eficcia Vacinas dessas na diminuio cases of cancer of the oropharynx, then everyone is voc estiver com alguma leso em sua of mouth try logo o seu dentist, but before INSCREVASE em nosso canal deixe o seu like, Compartilhe this video and for mais informaes acesse or nosso site!

Muito obrigado ! . 10 home remedies for cold sores on the lip or fire 10 home remedies for cold sores or fire Cold sores or fire is caused by contaminated herpes virus usually smplex type 1, which is spread by contact, for example, through a kiss or by using elements as razors, towels and other items that are shared. 1 Apply plstica bag of ice wrapped in a towel, feeling the first tingling of herpes labialis in order to reduce inflammation. If you do not have at hand an ice pack, you can spend. Ice cube directly in the area. 2 Apply directly a bag of black t to soothe the burning. 3 Clean daily blister cold sores with the pulp of a tomato and after applying aloe vera which help dry the affected area. 4 Soak a piece of cotton cloth with witch hazel and apply several times a day in order to dry out the sores or rashes. Avoid passing these paos by other body parts as they can infecting them. 5 Soak a piece of fabric with one or two tablespoons of castor oil and then apply. About the area where the cold sore is located.

6 Place the lip where is located the blister vesicle 2 drops of essential oil of the tree of t every 15 minutes. This oil is considered an antiviral prevents the virus develops and therefore, the symptoms disappear quickly. Cure from the aromatherapy 7 Extract the juice of a lemon and apply a few drops directly on the outbreak. Perform this operation 3 times a day. 8 Put some ash over the area. Dry, cracked heels remedy With the arrival of summer began to take off our clothes and also began to take off our shoes closed over time to wear sandals heels we see that we are doing may appear dry and even the antiestticas and painful cracks. So. What deberamos have done Deberamos taking zinc supplements essential fatty acids or omega 3, 6 and 9 because it can be for a deficit of vitamins and minerals. But if you already have chapped heels, we are going to give a shock treatment to avoid them. What we will use will use vegetable drink Avena. Oat is a cereal that is very soothing. We will soften these so parched and as vespers areas while we calm if and tuviramos cracks.

And we will incorporate shea butter. Let’s put warm milk oats in a rapping. Also you can do this remedy by mixing half water and half oatmeal or only with water and will incorporate a nut shea butter. The shea butter is. Originating from a tree of African origin and has moisturizing, nourishing, softening and properties. in addition it has a high anti-aging power. So we’re going to protect, moisturize and nourish. Let’s put a knob of butter Karit to be melted right away because it melts at 28 degrees. It only contact with our hands be melted. We’re going to mix everything in a vammos rapping and put our feet in about 20 minutes. From there we are going to take, we’re going to dry and we will take. Home Remedies For Mouth sores Natural Treatment for Cold Sores Home Remedies For Mouth sores Natural Treatment for Canker Sores, Home remedies for sores are very effective, fciles to prepare and very econmicos.

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