Overview More than 85% of adults have serologic manifestations infections of herpes simplex virus type 1 (HSV-1) acquired more often without symptoms in childhood. Sometimes, primary infections are manifested by Gingivostomatitis serious. Later, the patient may have recurrent episodes disappear spontaneously, caused by exposure sun, orofacial surgery, fever or a viral infection. Almost 25% of the US population has serologic data infection with herpes simplex type 2 (HSV-2) virus, which causes lesions whose morphology and evolution are similar to
those caused by HSV-1 in the genitals of both genders. The infection is acquired by sexual contact. In heterosexual couples monogamous, in which one partner is infected HSV-2 seroconversion occurs uninfected partner in 10% in the course of a year. Apparently, up to 70% of these It transmitted infections during periods of asymptomatic shedding. Genital herpes can also be caused by HSV-1. _ Clinical manifestations A. Signs and symptoms
The main symptoms are burning and itching. The episodes may preceded or accompanied by neuralgia. The lesions They consist of small vesicles grouped that may appear anywhere, but more frequently in the vermilion border the lips, the body of the penis, lips, perianal skin and buttocks (Figs. 6-18 and 6-19). Any erosion region perhaps due to genital HSV-2 (or HSV-1). Lymph nodes Regional perhaps are swollen and sensitive.
The lesions usually they form scabs and heal in a week. herpes Simple is the most common cause of painful genital ulcerations in individuals with immunodeficiency virus infection B. Laboratory data Herpes simplex lesions should be differentiated from chancroid, syphilis, pyoderma or trauma. Antibody tests Immunofluorescent provide direct on slides sensitive, rapid diagnosis. It is also useful for viral culture.
En2011 121 diagnosis of acute genital ulcer, serology not used herpes. However, the specific serology of HSV-2 by immunoblot analysis (Western blot) or enzyme-linked immunosorbent assay (ELISA) allow What people are infected with HSV and have infectious potential. This study is very convenient in pairs in which only one partner refers a history of herpes _ Complications Complications include pyoderma, eczema and herpetic whitlow, gladiatorial herpes (herpes epidemic in lifters
weight transmitted by contact), proctitis, esophagitis, neonatal infection, keratitis and encephalitis. _ Prevention Sunscreens are useful adjuncts to prevent recurrence sun-induced. Prophylactic use of oral acyclovir often avoid recurrences; should be administered in doses of 200 mg four times a day, starting 24 h before exposure to light ultraviolet buccolabial dental surgery or cosmetic surgery. Dose are comparable valaciclovir, 500 mg every 12 h, and famciclovir, 250 mg twice daily. _ Treatment
A. Systemic treatment There are three systemic drugs for treatment herpetic infection: acyclovir, valacyclovir your valine analogue and famciclovir. All three drugs are very effective and, when used properly, they have almost no toxicity. Alone Acyclovir may be administered intravenously. except buccolabial severe herpes in immunocompetent patients, only genital disease is treated. In the early episodes
clinical herpes simplex, acyclovir dose is 400 mg orally five times daily (or 800 mg every 8 hours); the valacyclovir, 1000 mg every 12 hours, and famciclovir 250 mg three times a day. The duration of treatment is seven to 10 days depending on severity the outbreak. Almost all cases of recurrent herpes are mild and require therapeutic measures. Furthermore, pharmacotherapy against recurrent HSV has little benefit; studies, an average reduction of only 12 outbreaks were observed 24 h. To be effective the treatment, the patient should start as the first sign of recurrence appears.
If you desired control outbreaks of recurrent genital herpes, this can be out three days valaciclovir 500 mg twice daily, or five days of acyclovir, 200 mg five times a day, or famciclovir, 125 mg every 12 h. Valacyclovir, 2 g twice a day one day, or famciclovir, 1 g once or twice in a day, are other treatments short they offer the same effectiveness and can stop impending recurrences both genital herpes as buccolabial. The addition of a potent topical corticosteroid three times a day reduces the duration, size and pain of herpes buccolabial treated with an antiviral medication orally. In individuals with frequent or severe recurrences, it is very
effective suppressive treatment to control the disease; reduces outbreaks in 85% and decreases viral shedding in more 90%. This results in a reduced risk of transmission almost 50%. Suppressor recommended doses, they continuously provided, are: 400 mg of acyclovir, Valaciclovir 500 mg, or 125 to 250 mg of famciclovir, every 12, 24 and 12 h, respectively. Apparently, the long-term suppression is very safe and after five to seven years a significant proportion patients may discontinue treatment. The use
condoms and instruction of patients have reduced transmission of genital herpes according to some studies, but in others there has been no benefit. No intervention alone or combined absolutely prevents the transmission. B. Local Measures In general, topical treatment is ineffective. It is recommended firmness acyclovir ointment 5%, if any is used, limit restricted the indications for which it is approved, ie initial genital herpes infections and mucocutaneous of herpes simplex in immunocompromised patients.
The application penciclovir cream at the first sign of herpes buccolabial recurring every 2 h, when the patient is awake during four days, the average duration decreases episode five to 4. 5 days. _ Forecast In addition to the complications described, recurrent episodes last several days and patients recover without sequelae.
Herpes Simplex is a viral disease, have suffered from the millions of people. Herpes can occur at any time, with people of all ages, regardless of gender. Why is that? we want precisely this question here pursue in www. Herpes24. de together with proposals for targeted treatment approaches so that the herpes disappears as soon as possible! A herpes disease by both the herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2) induced. The incidence of disease recurrence of cold sores can vary greatly, from once every few years to several times a year. Herpes Simplex is the medical name for a group of different viruses. This group includes the varicella zoster virus (which chickenpox and herpes zoster triggers), the Epstein-Barr virus (resolves glandular fever = mononucleosis from), the cytomegalovirus (Cytomegalovirus, mainly affects newborns and chronic immunodeficiency), and the herpes simplex virus that cold sores and genital herpes triggers. Herpes Simplex – Causes Are the herpesviruses once in the body, they beiben a lifetime there and are inactive until they from time to time again “awaken” and the usual herpes symptoms are recognizable. Recurrent herpes simplex infections (which tend to be less pronounced than the primary infection), can be triggered by a number of factors – but the new disease is totally unpredictable for most people.
Among the causes of cold sores can (among others) are counted: stress immunodeficiency sunlight Menstruation Alcohol or drug abuse Serious diseases (for example, cancer, HIV, etc. ) The most common types of appearance of herpes simplex disease are: Cold sores, whose visible symptoms is also called cold sores or Bläschausschlag; relates Ask around in and around the mouth, and is the most common form of herpes infection. Genital herpes is the second most frequently occurring disease with the herpes virus and affects the genitals and surrounding genital regions. Herpes Zoster (is not caused by the herpes simplex virus, but triggering the chickenpox varicella zoster virus), also known as shingles, is an inflammation of the nerves, in which forms a painful, large-scale eruption. In the interest of successful herpes treatment!
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