Herpès: traitement, Symptômes, de quoi s’agit-il?

Est une maladie L’herpès virale pair traduit qui l’apparition of vésicules petites groupées. Il s’agit d’une maladie et il contagieuse in there deux types, lip (bouche) et génital (sexuels organes). Sa wide contagion, l’une maladie à herpès est près Surveiller to pour ne pas qu’elle is PROPAGE. Retour sur ce virus, ses causes, modes of transmissions, et comment traiter him. Définition: Qu’est ce que l’herpès? L’une maladie herpes is due contagieuse virale et l’au virus herpes simplex virus (HSV) caractérisée par des affections of peau et des mucous membranes. In présence d’herpès sur des vésicules groupées apparaissent the touchée zone. L’herpès is a virus, il deux types in there, l’herpes simplex virus type 1 (HSV-1) responsible for l’Cold Sores, et l’herpes simplex virus type 2 (HSV-2), qui concerne l ‘ Genital herpes. L’herpès poussées pair manifeste. Vésicules sont les effet visible 6 à 10 jours pour plusieurs mois pendant disparaître jusqu’à réapparaître. L’est une genital herpes infection transmissible sexuellement (IST), elle apparaît sous forme de petites douloureuses vésicules south sexuels you organes them. Selon la région du globe de 50 à 90% of déjà été population aurait infectée par le HSV-1. The avant première lieu infection ayant 20 ans, souvent lors de la petite enfance.


Cependant the majorité des personnes mais celui détiennent virus ci le reste inactif. L’au HSV-2 infection is différente, elle à l’âge survient généralement adulte between 20 et 40 ans. In Europe l’est peu répandu genital herpes, il est très cependant commun en Afrique, où 30 to 40% of the population is infectée, allant jusqu’à 90% même dans certaines régions. Causes: d’où l’provient herpès? Le virus de l’est très herpès contagieux. Notamment pour les personnes n’ayant jamais été au confrontées virus, ainsi que les femmes enceintes nourrissons them. Concernant l’herpès dans sa globalité, the transmission période de risque est à plus the vésicules lorsque sont les éclatées. From ce moment, tout ce qui into contact avec la plaie potentielle est une source of transmission. Il faut noter tout de même peut être that dormant virus, c’est à dire qu’une personne peut détenir virus sans l’avoir le contracté, et le transmettre via the salive ou autre, sans être conscient. Concernant le HSV-2, genital herpes ou, le plus souvent l’herpes au moment de rapports vaginaux anaux ou avec une personne non protégés infectée déjà repand. Lors of pénétration contenus dans les virus pénètrent vésicules them corps de leur nouvel him hôte par des lésions sur la peau microscopiques present ou par mucous membranes them. Néanmoins, il est impossible de contracter par l’GENITAL HERPES contagion indirecte, c’est à dire in étant in contact avec des objets préalablement utilisés infectées par des personnes (toilettes, serviette, eau . .

. ) car will rapidement une fois virus dies en dehors du corps. Plus rarement, chez les adultes, ainsi que les baisers contacts them sexuels oraux / génitaux main sont les voies de transmission. Il arrive aussi that virus sur le même transmette hôte, par exemple le peut être virus transmis par les doigts, des organes génitaux à la bouche ou aux yeux. Ainsi, l’peut causer cold sores genital herpes, et inversement. Quels Symptômes sont les de l’herpès? Cold Sores: Lors d’première crise of Cold Sores the plupart du temps il n’y a aucun symptôme. Éventuellement, et notamment chez le jeune enfant, la bouche dans son ensemble peut être atteinte, Menant à une gingival somatie aiguë. Les Recurrences (periods of réactivation de l’herpès) elles sont précédées of picotements, démangeaisons, sensation of brûlure, gonflement sur le bord des lèvres, ainsi qu’un général comprenant une malaise fatigue et de la fièvre. Après quelques heures à un jour of rouges et petites vésicules douloureuses apparaissent autour de la bouche. Remplies Liquide, finissent éclater par elles, elles forment puis une croûte. Genital herpes: Genital herpes is caractérisé L’sensiblement même manière of cold sores that l’à l’exception de l’apparition of enflés ganglions à l’aine. Poussée à la suite d’herpès of vésicules petites apparaissent.

Chez l’on peut constater homme sur ces vésicules pénis him fesses them, you scrotum, cuisses them, l’anus, et l’urètre. Chez la femme à l’on finds them entrée du vagin, sur les fesses, south vulve et sur le col de l’utérus. Traitement: l’herpès soigner comment? Il n’existe aujourd’hui encore aucun traitement éliminant le virus du corps définitivement. Il s’agit soigner alors of them uniquement à l’aide de Symptômes médicaments lorsqu’une crise Surgit. Parmi eux le paracetamol, crème à l’acyclovir, docosanol au . . . Concernant l’genital herpes, you traitement est le même, cependant lorsque sont les crises fréquentes, peut le médecin prescrire des différents pour une durée DOSAGES prolongée, ou d’un an plus. The prize de ces sur le long terme médicaments permet of crises Réduire them, voire de les faire cesser, mais aussi le diminuer conséquemment risque de transmission, réduisant le risque de récurrence of 85 to 90%. Attention à ne pas utiliser of crèmes en vente free, et notamment celles à base d’antiviraux. Celles ci ne l’s’utilisant to pour cold sores.

Is it contagious canker sore?

Image: www. consejos-de-belleza. com mouth sores Different types of sores can appear anywhere within the mouth. Some of the places where cold sores can occur are: The back of the mouth The inside of the cheeks gums The lips Language Causes Mouth ulcers can be caused by irritation following:

A sharp or broken tooth or poorly fitting dentures Biting your cheek, tongue or lips Burning your mouth from hot food or drinks use braces chewing snuff Cold sores are caused by herpes simplex virus and is very contagious. You usually have tenderness, tingling or burning before the sore actually appears. Cold sores usually starts as blisters and then crusts. The herpes virus can live in the body for years and appears only as a canker sore when something active, such as: Another disease, especially if there is fever hormonal changes (such as menstruation) Stress Sun exposure

Canker sores are NOT contagious and can appear as a pale or yellow ulcer with a red outer ring. You can have one or groups of these lesions. Women seem to collapse them more than men. The cause of canker sores is not entirely clear, but may be related to: A weakness in the immune system (eg by cold or flu) Hormonal changes Stress Lack of certain vitamins and minerals in the diet, such as vitamin B12 or folate. Less commonly, mouth sores can be a sign of a disease, a tumor or a reaction to medications. This may include: Drugs that can cause mouth sores include acetylsalicylic acid (aspirin), beta blockers, chemotherapy drugs, penicillamine, phenytoin and sulfonamides. Home Care Mouth ulcers often disappear in 10 to 14 days, even if you do nothing.


Sometimes they last up to 6 weeks. The following measures can make you feel better: Avoid hot foods or drinks, salty or spicy foods and citrus Gargling with cold water or salt Eat popsicles, which is helpful if you have burning in the mouth Taking painkillers such as paracetamol For canker sores: Apply a thin paste of baking soda and water on the ulcer. Mix 1 part hydrogen peroxide (hydrogen peroxide) with 1 part water and apply this mixture to the lesions using a cotton swab. For more serious cases, treatments include fluocinonide gel (Lidex), the anti-inflammatory amlexanox paste (Aphthasol) or mouthwash of chlorhexidine gluconate (Peridex). The non-prescription drugs, as Orabase, can protect a sore that is inside the lips and gums. The Blistex or Campho-Phenique may provide some relief from cold sores and fever blisters, especially if applied when the sore appears inicialmente. Para help cold sores or fever blisters, you can also apply ice .

Call your provider Call your doctor if: The sore begins soon after starting a new drug It has large white patches in the mouth or tongue (may be thrush or other infection) The mouth sore lasts longer than 2 weeks You have a weakened immune system (eg, HIV or cancer) You have other symptoms like fever, skin rash, drooling or difficulty swallowing What to expect at the doctor’s office The doctor or nurse will thoroughly examine and review the mouth and tongue. Questions will be asked about your medical history and symptoms: Treatment may include: A drug that insensible area as lidocaine to relieve pain (do not use with children). An antiviral drug to treat herpes lesions (however, some experts do not think the drug does away with ulcers before). Steroids gel applied on the ulcer.

A paste reduces swelling or inflammation (as Aphthasol). A special type of mouthwash as chlorhexidine gluconate (Peridex like). Prevention You can reduce the chance of getting common mouth sores: Avoiding very hot foods and drinks Reducing stress and practicing relaxation techniques like yoga or meditation chewing slowly Using a toothbrush soft bristle Visiting your dentist immediately if you have a sharp or broken tooth or ill-fitting dentures If you seem to develop canker sores often, talk to your doctor about taking folic acid and vitamin B12 to prevent outbreaks. To prevent cancer of the mouth: Do not smoke or use snuff. Limit alcohol intake to two drinks per day.

Wear a wide-brimmed hat to protect lips from the sun all the time and use a lip balm with sun protection factor of 15. alternative names aphthous References Daniels TE. Diseases of the mouth and salivary glands. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011: chap 433. Source: http://www. nlm. nih.

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What is the Natural Cure for Cold Sores?


Once infected, the cold sore virus remains dormant for long periods and can be reactivated. Episodes of cold sores rarely last more than two weeks. The sun, wind, cold or depressed immune system can cause reactivation of the symptoms of cold sore virus. For this reason it is said that lipstick is a recurring herper Sexually transmitted diseases. I recommend you visit a doctor, for when you have symptoms. What I can recommend is a program that I followed and I was super well have not appeared sores on my body for a long time and have not had to use acyclovir anymore, there I leave a link with the program. I hope it helps you Check here the best natural treatment to cure cold sores, shingles or genital. Cheer up! To cure herpes, the first thing you have to do is not tocártelo much, lest they infect you and you remain marks herpes, or you hurt yourself in the area. Although disturbed or even you will want, Leave it on alone. Then, if you want to cure herpes and do well, it’s best to turn to natural remedies. Herpes has been around since long before the medicine and there are few remedies for herpes world.

I leave here a link to a very good, that you will take a look. A greeting! Abrela purchase pinicilina in capsule and powder you put in the area where you have herpes and for safety you can also inject both simultaneously bye and good luck Of course if you have a cure, in fact, the treatment is very effective and not very expensive. However, there are some genetic factors difficult to control, in each person. That predispose to this disease by periodic episodes. Herpes can not be cured because it is a virus microorganisms living within a cell by which our immune system does not detect and does not create antibodies, but if you are attacked with some drugs such as acyclovir which is available in pharmacies virus this how the virus returns to its normal state within the cell. The herpes appear and disappear can take years and reappear and usually coincides with low defenses No cold sores usually is caused by virus Hepres Simplex type 1 (although the type 2 also can cause), these viruses belong to the family of Herpesviridae, encapsulated, icosahedral formed of two DNA strands) them to like their close cousins ​​(Varicella zoster, and Epstein Barr virus cytomegalovirus virus), are the most common viral diseases in young adults. Herpes at the same time that contagias you are staying with you and those predisposed to it at any time have a reactivation of the virus, it is estimated that 90% of people for the fifth decade of life (40 years) and have antibodies against this virus, despreocúpate all have it, the problem is that not everyone has the reactivation of the disease, should talk to your doctor to suggest how to avoid reactivating just make a paste with a little lemon juice and baking soda you will burn a bit but is very effective. Check here the best natural treatment to cure cold sores, shingles or genital.

Herpes

–> Shingles is a viral infection caused by the sensory nerves of the causes of theskin and a painful skin rash. The forshingles medical name is “herpes zoster”. That makes the herpes zoster virus is thesame virus that causes chickenpox (varicella). KEYWORDS to search the Internet and other reference sources Dermatology Infectious diseases Virus zoster What is shingles? A person can not develop shingles unless he or she has had chickenpox. Shingles is caused by the same virus that causes chickenpox, herpes zoster virus.


While chickenpox is a highly contagious disease, shingles usually not spread from one person to another. However, a person can develop chickenpox in direct contact with the blisters in a person with herpes zoster. After recovering from chickenpox, herpes zoster virus may remain in a part of the nervous system for years without causing any disease. Shingles can be the product as a side effect of another condition, such as Hodgkin’s disease (cancer of the lymph system), or treatments that suppress the immune system *. However, most of the time, there is no known cause for the virus to become active and cause shingles. * The immune system fights germs and other foreign substances that enter the body. –> What are the symptoms of shingles? The affected skin feels sensitive area, and then becomes painful. Before the shingles blisters develop, the person may have fever and chills, feel tired and have an upset stomach. These symptoms can last from 3 to 4 days. On the fourth or fifth day of the rash of small red spot appears. Small red spots turn into blisters that are the herpes zoster virus.

After a few days, the blisters turn yellow and October Develop dried crusts on the blisters dry. When They Several weeks after leaving, sometimes leaving small scars. Usually, the rash and blisters involves a limited area of ​​the skin, most often on one side of the chest, abdomen or face. What is the treatment for shingles? Treatment for shingles is directed mainly involved in pain reduction. Medications are used to also attack the virus. Wet compresses applied to affected areas can sometimes relieve pain. mild analgesics such as acetaminophen can be used. Who is at risk for shingles? Shingles occur primarily in older people whose immune systems are no longer able to keep the virus dormant in the nervous system. This age group most often develops herpes zoster, shingles can develop at any age, though. After an attack of shingles, a person can be immune for the rest of your life. Most people recover from the illness without any problems.

However, in elderly patients, the pain can last for months or years after the blisters have healed. This is known as post-herpetic neuralgia (post-her-PET-ik noo-RAL-gee-ah). What other diseases can cause herpes zoster? The herpes zoster virus can cause several other diseases: Chickenpox is usually a mild disease that causes a rash and fever. It is very contagious. Otic herpes zoster, also called Ramsay Hunt syndrome and viral neuritis, causes earache, hearing loss, vertigo (sensation of rotation), and can paralyze the part of the face. ophthalmic herpes zoster involves the eyelid and the eye itself can sometimes be severe if the eye is involved.

Effects of emotional stress on oral health – Center of Modern Dentistry


In addition to the heart and psychological health, emotional stress can cause effects on oral health of any individual. The anxiety caused by the disease can significantly affect teeth. Emotional stress affects the immune system; This is responsible for combating the bacteria that cause periodontal disease making the chances of gum infections are higher. Several studies have confirmed that emotional stress causes oral infections, inflammation in the gums, bone loss and common bleeding gums that many perceive. A specific study conducted at the University of Michigan confirmed that those with emotional stress linked to financial problems, were those with higher indicators periodontal diseases. Emotional stress caused by family, work, and especially money lead to severe periodontal disease. However, those who were dealing with this stress in a healthy way, they had both disease risk. Aside from periodontal diseases, emotional stress can also cause mouth ulcers, which are indicators of the weakness of the body by stress. Due to emotional stress, many people tend to increase the intake of foods such as sugars that increase risk and damage dental health. It has even been shown that the buccal mucosa is highly influenced by psychological stress. So much so that this is characterized as the second leading cause of damage to the teeth and oral cavity. In addition, in recent years it has found a close relationship between the incidence of caries and emotional stress. Other of the many effects of emotional stress are:

Bruxism (teeth grinding) Tooth wear Fatigue in the muscles of the jaw Herpes labialis Gingivitis Effects of emotional stress on oral health

When you know how to remove Cold Sores in 1 day in children and adults


Cold sores are a fairly common occurrence when we are children, often happens when defenses are down by certain factors that cause their appearance, can also bring other symptoms such as pain or fever. These herpes is a type of virus that usually appear on mucous membranes, nerves or skin and, as mentioned above, it is a simple herpes which appears when we are children. Mainly it is shown as vesicles that can appear both inside the mouth and around, causing great discomfort and pain. When they appear inside the mouth they look like small white ulcers, while around, look like blisters with a clear liquid inside. Being a fungus, the infection can cause fever disease in children up to 39-40 degrees. Also difficult to feed the child, because having him in the mouth, the pain is very intense and limited movements with his lips. We must be very careful with these herpes, as they can about infected, causing many more problems as the spread of the fungus. How children are infected and how to treat it? The main cause of this infection is by the saliva of someone with the virus, it falls on the child’s lips causing the appearance of herpes when the child has low defenses. There may also be spread by sharing eating utensils or kissing people who have the virus. The child may also become contagious through saliva, let it be when it ceases fever. For the treatment of this fungus first thing you should do is the following: Apply alcohol at 70 °. It is a simple method and it works better than creams antivirals, you just have to apply it with gauze between four to five times a day and herpes it disappears without the scab appears.

In the case of occurrence of crust and is often broken by the use of lips, petrolatum can be applied to provide elasticity. Like you should visit the doctor if your child has this type of herpes, you can help you discover what it is and how to treat it. Feel free to share and comment.

What is it? ¿Chicken pox, rubella, scarlet fever or measles?

connections What is it? ¿Chicken pox, rubella, scarlet fever or measles? Eruptive are a group of infectious diseases peak incidence in early spring. Not all have the same symptoms and risks and have different treatments. How do you tell them apart? Mariana Nisebe Of the Writing of Clarín. com When we are children almost all we suffer some eruptive disease. Or we had the experience or have heard something about it. But how do you differentiate? Not all have the same symptoms or the same treatment, even the same risks. They are so called because they surface skin blemishes, pimples or blisters; simulating similar to volcanic eruption.

The pediatrician will interpret whether it is an eruption of the skin and its relationship or not with an infectious disease or an allergic reaction, among other possible causes. Like all eruptive diseases, it is preferably in the autumn, late winter and especially in spring. Yes, in the spring! Chickenpox So you have to be attentive and above any suspicion, consult your doctor. Chickenpox is the easiest to recognize, because “it presents with fever and skin rash with blisters and scabs all over his body,” according to a report by Ricardo Gutiérrez Children’s Hospital. Moreover, they add, “is very contagious, is transmitted from person to person through contact with the skin lesions and secretions such as mucus or saliva of an affected between 2 days before the first blister person and up all these are like scabs. During this period the child can not be in contact with other children or pregnant women who have not had chickenpox. ” It has an incubation period of 14 to 16 days and lasts about 10 days on average, although there are cases of up to 21 or more (immunocompromised). Chickenpox is, today, the most common childhood infection eruptive. “In our country are estimated to occur between 350 and 400 thousand cases annually. The virus that causes it, Varicella-zoster, is acquired in childhood and remains” asleep “or dormant in the body for the rest of life. In advanced ages can “wake up” or reactivate, and produce “shingles”, medically known as herpes zoster, “describes Dr.

Claudia Vujacich. It is noteworthy that T here is a vaccine made with live attenuated virus and Varicella-Zoster, with an efficiency of up to 98% and a minimum of side effects; but today is not found in National Immunization Schedule. Their cost ranges from $ 130 to $ 150 (depending on brand). And, although generally does not produce complications, experts explain that it is dangerous in infants and immunocompromised adults. According to a national study published in 2005, “within the complications encountered we are: (most common) bacterial infection, bacteremia, acute otitis media, bacterial varicella pneumonia, pneumonitis, encephalitis (rare in children), acute cerebellar ataxia, Reye’s syndrome , hemolytic uremic syndrome and myocarditis “; so the authors believe i ncorporar suitable vaccine mandatory calendar. Treatment of chickenpox can include everything from painkillers (not to use aspirin), antihistamines and creams or lotions that soothe itchiness (its effect is palliative and transient); to antiviral drugs (for severe cases). The bottom line is preventive treatment by vaccination. Rubella Rubella, meanwhile, is also a viral disease that affects children and adults; but “is characterized by the appearance of pink spots that begin in the head and down to the body, accompanied by fever and enlarged lymph, especially in the neck and behind the ears,” reports the Ministry of Health of the Nation, which has just launched the National Campaign for the elimination of congenital rubella syndrome. This condition occurs in 90% of children born to mothers who have had rubella during the first trimester of pregnancy; It is causing severe damage to the baby. In general, except in the case of a pregnant, l as complications in the course of the disease they are rare. In fact, “25 to 50% of patients do not show any signs of illness. When the rash is present, it is often indistinguishable from other viral infections such as enterovirus infection, fifth disease or mild measles, among other .

so no one can confirm the diagnosis of rubella without a blood test, “Liliana Vazquez described in a report published by the Foundation Center Infectológicos Studies (FUNCEI). The virus is transmitted through saliva droplets that are released into talking, coughing or sneezing or through contact with contaminated secretions objects; and the incubation period ranges between two and three weeks before symptoms appear. Contagion another person may occur from one to two days before the rash appears until a week after it started. Currently there is no specific treatment for rubella virus. As measures are basically the symptom relief (analgesic – antiinflammatory). The vaccine is the most important measure of prevention. Scarlet fever It is the only eruptive bacterial, so it is treatable with antibiotics. It is caused by group A streptococcus The rash is characterized by many colored spots that are joined together and sometimes make all the skin is red. When touched, it feels like goosebumps or grater, and itchy. In an early stage of the disease, the tongue is covered by a layer of yellowish-white through which a red buds appear, which give an aspect of “strawberry tongue”. N ormally is accompanied by an inflammation of the pharynx (throat), tonsils (tonsillitis) and fever. You can even give chills, joint pain throughout the body, nausea, vomiting and loss of appetite.

A child who has scarlet fever can spread the bacteria to others through nasal secretions and throat breathing and sneezing. If it is confirmed that you have an infection (with exudate fauses), the doctor will prescribe an antibiotic to be taken for about 10 days. Measles Finally, a space for this highly contagious viral disease, whose symptoms usually appear in two stages. In the first, fever, runny nose, red eyes and coughing it arises. The second stage begins around the third to seventh day a red rash that begins to appear on the face and spreads over the rest of the body. Small white spots, called Koplik spots, can also be seen on the gums and inside the cheeks. Incubation is 8 to 14 days before the onset of symptoms. A person with measles virus can spread from two to four days before the rash appears and until the rash disappears. The picture resolution in two weeks is usual when complications do not appear; which can be, s ccording to a report by the Hospital Italiano de Buenos Aires, “or half marmosets, laryngotracheitis, tracheitis, bronchitis, pneumonia and encephalitis. ” The last measles cases were observed in Argentina in Cordoba in February 2000. In 2002 and 2005 the “follow-up campaign” was conducted throughout the country. So far, there is no documentation of measles virus circulation in the country; so its eradication is sought; hence the importance of vaccination and strict controls to cases not matter.

Shingles – Informative article Rafael Sánchez

Shingles Rare is the person of adult age who has not had chickenpox. Well when a child or youth, have almost all had that disease characterized by itching, warmth, blisters on the skin and in which we recommended (much to our regret) not wash scratching or pain of leaving scars. Over the years, we just forget about it and just commented at some point, “and I spent chickenpox”, without realizing that it may actually have not gone entirely, ie, which is still active within US. latency Those who have families in the villages or who had someone older person nearby, you may on occasion they have heard of “shingles”, an itchy with redness of the skin begins to curl up by the body (usually chest) and according to the popular tradition, if completely screwed and closes, it can cause death. Reality is not so dramatic. At least today. That “shingles” is nothing other than the shingles, and this is only a reactivation of the chickenpox virus. Once you have had chickenpox, although the immune system removes almost all of the body, is latent in the nerve ganglia, dorsal both as trigeminal. The virus can remain in that state for a long time, but when the immune system is decreased (either by a disease, a situation of stress, lack of sleep, etc. ), the virus reactivates and replicates in neurons (the nerve) cells, and although again causes chickenpox, it does affect nerves. It is at this time when we noticed swelling of the skin with blisters and nerve pain due to irritation of the nerves affected.

There are people who do not show clear symptoms in the skin, but most complain of headache, fever and pain (sometimes very strong) in the area where spots appear then be turned into vesicles. If the herpes develops in the eye area, you must be especially careful because it can affect vision. Contagion Zoster, as has been said, is the chickenpox virus. It is passed by direct contact. That is, you need to touch the vesicles of an affected person to become infected. It is not spread by breathing. Obviously, if the infected person has not had chickenpox, instead of also developing herpes zoster, which is a Varicella develop. The virulence of this will depend on the immune status of the recipient. What to do? When a table has been medically diagnosed as herpes zoster occurs, aid that can be offered must pass from natural techniques, basically by stimulating the immune system to take charge of controlling the virus. Since homeopathy, can be treated with Rhus Toxicodendron (the principal in these cases, given that a picture of paroxysmal itching, vesicular edema, burning, red skin with blisters with liquid inside them that worsens with cold presented) , Cantharis (to appear online vesicles and burning sensation and itching) or Mezereum (vesicles that form white scabs and itching worse at night). It is advisable that homeopathy is accompanied (especially if it is not led by a professional) with supplements such as vitamin C (as long as there is no intestinal problems), Lysine (a highly recommended amino acid in cases of shingles because of its antiviral power ), trace mineral copper (for viral infection of any type), vitamin B12 and Germanium sesquioxide shaped.

While shingles has a very bad reputation and thus the term “ringworm” was coined, we must remember that the immune system is critical in this case, and it was not always in the past, may increase so that it could adequately combat envites of any type of infection. Either ways, although you must lose fear, we must be careful, because it can be a very annoying, painful problem and should be treated as soon as possible. By Rafael Sánchez Naturopath Madrid Remember that you get a 5% discount on the total purchase For more information see Volume purchase you can choose your gift For more information see

Veterinary vision

WATERFALLS October 13, 2007 Leave a comment Veterinary Vision WATERFALLS The lens is transparent in normal conditions, when this transparency is lost and opacities say there appear cataracts. Cataracts do not allow normal passage of light to the retina and can not be “translate” the images in the brain as impulses that reach him were incorrect. If we look at our pet front will see the center of the iris, where the pupil is located (in black under normal conditions) white (larger or smaller depending on the intensity of light or the severity of the process) . Do not confuse the sclerotic cataract lens, normal in older dogs without clinical significance. Cataracts logically leads to blindness or reduced vision in the affected eye (depending on the state in which you are). Many animals are blind without the owner being aware of it, this happens because the animals are handled very well in familiar environments and with the help of smell, touch and hearing, as these animals out of their environment show great confusion and struck with the objects around them. Other consequences occur: – Facolítica Uveitis occurs in very mature cataract (Hypermature) due to its large size causes “out” of material from the lens into the eye, this material is very inflammatory and results in intraocular inflammation, is a dangerous process. – Glaucoma is an increase in intraocular pressure and may be due to facolítica or to secondary processes such as dislocations lens (the lens is clear from its usual location) uveitis, this process is very dangerous, sometimes causing increased eyeball and loss. There are many reasons why a cataract may appear: hereditary, metabolic, inlflamatorias, traumatic, perforated ulcers, toxic, etc .

. . Symptoms and characteristics: – Loss of vision – Change color of the pupil (white) – Dilated pupil – Sometimes red eye secondary to inflammation associated – Uveitis, glaucoma or hypertensive uveitis (in some cases) – Loss of natural lens position (dislocation) in some cases Forecast: Generally good if no associated ocular or systemic diseases. If retinal problems can be eliminated to avoid secondary cataract vision problems but will be very relaxed or destroyed due to the main problem in the retina. Usually a problem of geriatric animals so surgery must be well planned to avoid problems in anesthesia and surgery (heart, kidney, eye and existing)

Postsurgical complications depend on the general condition of the animal, as well as the character of our pet (very nervous dogs are more prone to problems) Treatment: Treatment is always surgical, eliminating the clouding of the lens. Medical treatment is applied before and after surgery, in most cases for life. Not all cataracts are operable not all dogs are candidates for this surgery, to do an independent study of each case to tailor treatment R. R. UDIZ INTERESTING LINKS ON FALLS http://www. infomascota. com/articulos/veterinaria/perros/2003/12/3/vet_cataratas/ http://www.

vetcontact. com/es/art. php? a=52\x26amp;t= http://www. foyel. com/cartillas/53/cataratas_en_perros_y_gatos. html CATARACT SURGERY: Phacoemulsificator IMPORTANT NOTE: This video may offend the sensibilities of some people [Embedded content] Optivet (Video posted on YouTube) Categories: FALLS

corneal ulcers October 12, 2007 Veterinary Vision 2 reviews Corneal Ulcers Ulcers are “wounds” of the cornea. There are several types of ulcers and may be caused by many entities. symptoms: – Eye pain (blepharospasm, the affected eye closed or habre with difficulty), pain is greater in shallow ulcers, however deep ulcers are less painful (but more dangerous ! ! ) – Red eye – Blue Cornea (corneal edema) – Corneal damage can sometimes be seen with the naked eye, but for diagnosis requires the use of vital dyes such as fluorescein. – General discomfort

– self-trauma Types of ulcers: – Superficial: Affecting the surface area of ​​the cornea and are extremely painful. They can be very extensive but the prognosis is usually good. Scarring is usually rapid under normal conditions in about 4 days there reepithelialization area. Certain animals have problems in healing such as the Boxer, these animals suffer known as indolent ulcers, that are slow to heal and even surgical assistance needed for this. There are more races with this type of ulcer. Do not confuse indolent ulcers with ulcers that do not heal, there is always to look for the root cause such as eyelashes or hairs that enter the eye (trichiasis) ectopic eyelashes (distriquiasis), ectopic cilia, entropion or ectropion, etc . . . – Deep: The next step of surface corneal ulceration is deepening. In these cases the prognosis is serious because of the possibility of perforation of the eyeball. All of them require surgical treatment and correction of the underlying cause.

This type of ulcer is less painful than superficial ulceration but is much more serious. Causes: – Injuries: either self-produced or by external agents (bumps, scratches, chemicals, foreign bodies, etc . . . ) – Eyelid Problems (entropion, ectropion, trichiasis, distriquiasis, ectopic cilia, tumors, etc . . . ) – Infeciones viral, bacterial or fungal – Secondary to other diseases such as corneal problems underlying deficiency tear, proptosis bulbi, buphthalmia (increased eyeball), etc . .

. Treatment: – Medical: instillation of eye drops to relieve pain, prevent secondary infections and promote corneal scarring. you should always try the main problem, for example, if we tear deficit establish medical treatment, and resort to surgery if necessary, such as in the presence of entropion, etc . . . – Surgical: superficial ulcers complicated, very large or beginning to deepen must undergo surgery. Deep ulcers are always operating room. Surgical possibilities are varied and depend on each animal (nictitans flaps, conjunctival flaps . . . ) Forecast:

It depends on the type of ulcer and its etiology. Superficial ulcers often have a favorable prognosis while deep gravity are always reserved prognosis. Corneal ulcerations IMAGES: superficial ulcers (secondary to trauma 1st and 2nd ectopic cilium) Ulcer bacterial (Pseudomonas) and viral ulcer (herpesvirus) deep corneal ulcers (descematoceles) R. R. Udiz Categories: Corneal Ulcers GLAUCOMA October 11, 2007 Leave a comment Veterinary Vision GLAUCOMA

To increased intraocular pressure above normal physiological values ​​without clinical signs known as ocular hypertension and when it is accompanied by clinical signs such as vision loss or intraocular damage is known as glaucoma. Hypertension can be pre-glaucoma step but not necessarily develop, certain animals suffering from elevated intraocular pressure and can develop long-term injuries (eg chihuahuas, yorshire . . . ). The normal intraocular pressure (IOP) in small animals is 15 to 25 mm Hg, when these values ​​are exceeded the optic nerve and / or retina is affected resulting in noticeable changes, which are detailed below. IOP greater than 30 mm Hg with clinical signs is sufficient for a presumptive diagnosis of glaucoma. Early treatment of glaucoma is essential for visual, glaucoma guarantee more than 24 hours cause irreversible effects (although there are variations according to animals affected). Often the vision is lost before the owner becomes aware of the problem, but still quick action can save the affected eye and preserve vision in the other eye. The causes of glaucoma are varied, and depends on the species: – Glaucoma in dogs can apararecer acute and usually racial. El character early treatment is vital for a good prognosis. Generally glaucoma in dogs is a bilateral entity so should study the eye that is not apparently affected.

– Feline glaucoma has a worse prognosis may be unilateral or bilateral and is usually associated with systemic infections (toxoplasma, coronavirus, immunodeficiency or leukemia). slowly progresses to become chronic, so it has sometimes happens inadevertido by the owner until the buphthalmia (enlargement of the eyeball) appears. The IOP control is more complicated than in dogs and usually ends in enucleation. – Equine Glaucoma: much less frequent than in the previous two species and is usually 4 types: primary glaucoma, congenital glaucoma secondary to anterior uveitis and secondary to neoplasia. Control of IOP in this species is particularly complicated. Predisposition: – Racial predisposition: Dogs (Huskie, Terriers, Retrievers, Cocker Spaniels, Schnauzer, Basset, Beagles, Chow Chow, Samoyed, Great Dane . . . ) Cats (Siamese and Persian) Horses (Appaloosas) – Dislocation of lens – Uveitis – Tumors

– Eye Injuries Symptoms and characteristics: The symptomatology depends on the stage of glaucoma (acute, subacute or chronic), so the owner can see is: Acute: – Eye pain (blepharospasm, eye or eyes closed) – Blue Cornea (eye color change by corneal edema) – Fixed and dilated pupil (mydriasis) – Eye very red (red sclera) – Visual Impairment – Anorexia and depression Subacute: – Eye pain (blefarsospasmo) – Blue Cornea – Blindness or visual impairment


– Deformed, fixed and dilated pupils – Very red eye – Anorexia and depression Chronic: – Variable Eye pain – Vascularization, pigment and corneal edema – Lenticular opacification – Red or very red eye – Blindness or visual impairment – Dilated pupils fixed and abnormal – Anorexia, depression, shyness or aggression – Increase the eyeball and Descemet appearance of fine lines (by species) There may be increased pressure without symptoms, this process is known as ocular hypertension and is not the same as glaucoma, hypertension can develop into glaucoma so that preventive treatment is recommended if necessary or eliminate the trigger for the same cause ( intense stress for example)

Forecast: Reserved depend on the primary cause of glaucoma, the stage in which it is located and animal species affected. The visual prognosis depends on early treatment. Treatment: The use of topical antihypertensives, oral and / or parenteral can control certain types of glaucoma, treatment is usually for life, even in a blind eye. You can resort to surgery if necessary, always associated with medical treatment. If uncontrolled glaucoma is recommended practice evisceration and intraocular prosthesis or enucleation place in certain cases. The use of protecting retina has had great results in long-term visual eyes, delaying the onset of blindness and even preventing their appearance. Acute glaucoma is an ophthalmologic emergency and requires early attention to obtain acceptable results. Early diagnosis is crucial for the maintenance of vision. In case of suspected glaucoma consult your veterinarian. R. R.

UDIZ IMAGES OF GLAUCOMA: Buphthalmia in a puppy with glaucoma in the right eye corneal edema in the right eye in an adult but with glaucoma Buphthalmia right eye in a cat post traumatic glaucoma INTERESTING LINKS ON GLAUCOMA CANINE: http://www. revistacanina. com/notas_revista/20/Glaucoma_Canino. html http://www. petsalud. cl/articulos/Glaucoma_canino.

htm Categories: GLAUCOMA FELINE HERPESVIRUS October 10, 2007 Leave a comment Veterinary Vision FELINE HERPESVIRUS / RHINOTRACHEITIS FELINA / FHV-1 The causative agent: feline herpesvirus type 1 (HVF1) is primarily responsible for respiratory and ocular manifestations large number of feline diseases. Predisposition: – Kittens or cats provenance street – Animals vaccinated with access to fresh air and contact with unknown cats – Parents of virus carriers (transmission to offspring) – Young animals with eye problems discussed and improve but reappear in adulthood (carriers) – New cat at home (carrying the virus) that infects the old cat Symptoms and characteristics:

– Sneezing – Respiratory problems – Fever – Anorexy – discomfort – Purulent crusting – Neonatal ophthalmia in young kittens (puppies do not open their eyes and are full of gummy) – Symblepharon (abnormal connections conjunctival other ocualares attached) – Synechiae (unions iris to other ocular structures) – Acute or chronic keratitis (Cornales ulcers, eosinophilic keratitis . . . )

– Corneal Kidnapping (black plate on the cornea) – Chronic tearing (red tears) Forecast: Generally good, but usually animals that remain carriers for life and may have relapses (not always with ocular symptoms) Treatment: Symptomatic with antibiotics, anti-inflammatory and antiviral. Using products that inhibit viral replication has been very successful in the long term to control the symptoms, both ocular and respiratory. It is important to understand that the disease remains latent for life and that under certain circumstances (eg stress) can be reactivated reappearing ocular symptoms and / or breathing. IMAGES OF EYE DISEASES CAUSED BY FELINE HERPESVIRUS: respiratory and eye symptoms in a kitten neonatal ophthalmia corneal kidnapping Geographical corneal ulcer

Categories: FELINE HERPESVIRUS PROLAPSE nictitating membrane gland October 8, 2007 Veterinary Vision Leave a comment PROLAPSE gland nictitating membrane Also known as cherry eye is a disease characterized by the appearance of a pink and rounded mass behind the nictitans in the medial edge of the eye, is a condition that is not painful, but something annoying about especially at the beginning, and self-trauma may occur. Predisposition: – Brachiocephalic breeds (flat faces) and English Bulldog, Pug, French Bulldog, Shitzu, Lapsa apso, shar pei, Pekinese, etc. – Generally puppies, elderly or immunocompromised animals. – May appear in cats, but is rarer than in dogs. – Animals with cartilage in the very long nictitans, everted, or important invested glandular hyperplasia immunosuppression. Symptoms and characteristics: – It usually appears first unilaterally and, in some cases, bilateral soon. – You can not give cause discomfort or apparent symptoms.

– The gland is responsible for 40% (some authors even suggest that 60%) of the total production of tears, while the prolapsed gland is practically non-functional, – It may be associated with corneal injury (depending on the elapsed time, teardrop level, self-harm, etc. ) – Yellow / greenish gummy sticky aspect may appear secondary infections deficit tear. Forecast: – They tend to respond well to surgical treatment, having a recurrence rate of about 20%. – There may be pathologies associated with cartilage nictitans predisposing to prolapse of the gland, in these cases surgical correction of this condition is necessary to prevent recurrence. – Never to be removed (only if associated tumors) and have always replenish in place under general anesthesia. – If the gland is removed keratoconjunctivitis sicca predisposes to suffer in adulthood (especially in predisposed breeds) Surgery: The gland is positioned back in place and is supported by suturing to prevent further prolapse. IMAGES: The first image corresponds to an eye with prolapse of the gland

nictitating membrane and the second the same eye after undergoing surgery to replace the gland in its normal anatomical location interesting links about prolapse of the gland of the nictitating membrane: www. veterinariaelparque. com. ar/. . . /Oftalmologia/6-Patologia%20de%20la%20membrana%20nictitante. doc http://www. petsalud.

cl/clinicas/casos_clinicos/Ojo_de_Cereza. htm Categories: PROLAPSE nictitating membrane GLAND Welcome to the website of Veterinary Ophthalmology October 7, 2007 Veterinary Vision Leave a comment Welcome to the Blog of Veterinary Ophthalmology Mrs. Raquel R. Udiz, resident in the Canary Islands, Tenerife. This space emerges in order to bring a little more this specialty to those owners who want to know more about eye disease that affects your / s pet / companion is. Gradually we will be adding clinical cases, photographs and detailing the main surgical techniques as well as resolving all those questions that emerge over time. For questions or suggestions write to e-mail: oftalmologiaveterinaria@hotmail. com

Greetings to all / as. Categories: Various Newer Entries RSS feed Categories PROGRESSIVE RETINAL ATROPHY (APR) (1) Ulcer INDOLENT (1) Corneal Ulcers (1) Horses and horses (1) Squamous CELLS IN HORSES (1) CATARACT: TALK OF SURGICAL (1) FALLS (1) DIABETIC CATARACT (1)

FALLS NOT OPERATED: COMPLICATIONS (1) BLINDNESS (1) FLAP nictitating membrane (1) Rabbits (1) Ophthalmological (DIAGNOSTIC PROCEDURES) (1) FACIAL descolgamiento DOGS EARS pendulous (1) DISTRIQUIASIS and ectopic cilia (1) PAIN EYE (1) ENTROPION FOLD BY FACIAL (1) ENTROPION SHAR PEI (1) ENTROPION: TALK OF SURGICAL (1) Enucleation (1) EPIPHORA CANINE: Excessive tearing (2)

ANIMAL glasses and contact lenses (1) GLAUCOMA (1) FELINE HERPESVIRUS (1) Vitamin A deficiency AQUATIC TURTLES (1) CRYSTAL dislocation and subluxation (1) MELANOSIS AND FUZZY IRIS MELANOMA FELINO (1) Neuro-ophthalmology (1) Pannus (1) Corneal DRILLING: CAT SCRATCH (1) Intraocular Prosthesis (1) PROLAPSE gland nictitating membrane (1) KERATOCONJUNCTIVITIS EOSINOPHILIC FELINE (1) KERATOCONJUNCTIVITIS SECA (QCS) (1)

Dermoid cyst (1) Dermoid cyst PALPEBRAL: TALK OF SURGICAL (1) Cysts uveal (1) HORNER SYNDROME (1) KIDNAPPING CORNEAL FELINO (1) Symblepharon (1) TURTLES (1) TRAUMA AND BODY EYE STRANGER (1) EYELID TUMORS (2) Uncategorized (2) Uveitis RABBITS (1) Miscellaneous (6) VIDEOS (3)

Medical Microbiology and Parasitology. Volume II: Section V. Virus: Chapter 61. Herpesvirus: Herpes 6

Available book full text in pdf version The rest of the parts of the book are also available in that format. If necessary you can download the product from Adobe “Acrobat Reader” to display the contents of the book in pdf format by accessing the following link: herpesvirus 6 Herpes 6 virus is the sixth member of the family of human herpesvirus and was first isolated in the laboratory of Robert Gallo at the National Cancer Institute in Bethesda, Maryland, USA, patients with a variety of lymphoproliferative disorders herpesvirus 6 . The human herpesvirus 6 is the sixth member of the family of human herpes virus was isolated for the first time, in 1986, in the laboratory of Robert Gallo at the National Cancer Institute in Maryland, USA from blood lymphocytes peripheral patients with a variety of lymphoproliferative disorders. The isolated virus was a lymphotropic and well distinguishable genetic and antigenic characteristics that differentiate it from all allowed herpesvirus hitherto isolated and placed in the subfamily b herpesvirinae virus. Properties virus The HHV6 genome DNA has a double-stranded, linear, with a size of 155-170 kbp and varies between different isolates. More recent studies, however, have revealed that the HHV6 is more closely related to CMV. It has been shown by analysis of the nucleotide sequence exists 66% sequence homology with CMV. It has been demonstrated by molecular biology techniques the existence of two virus variants: Variant A and B. Both differ in terms of biological, genetic and restriction patterns properties.

Most patients with sudden rash and like febrile illness seem to have HHV6 variant B. HHV6 isolates immunocompromised adult may belong to either variants and at least one patient found both virus variants. The virus has been isolated from peripheral blood mononuclear cells of patients with sudden rash, immunocompromised patients and healthy individuals. It has also been isolated with high frequency from the saliva of HIV-infected patients. The virus replicates in vitro preferably fetal or adult origin phytohemagglutinin-stimulated T lymphocytes. In infected cells they can be detected viral capsids at day 3 and mature virions after 5 days. Pathogeny The main target cell HHV6 appear to be CD4 + lymphocytes. Macrophages are persistently infected and may be an important reservoir. Transformed B lymphocytes, natural killer, megakaryocytes, glial cells, fibroblasts and epithelial cells are able to support the replication of certain strains of virus. Frequent isolations saliva herpesvirus 6 suggest that the virus resides and is removed from the salivary glands. The viral DNA and antigens have been identified in epithelial cells of the salivary glands and from different regions of the upper respiratory tract. So far it is assumed that herpesvirus 6 infection is transmitted by horizontal transmission, and there is no evidence of vertical transmission.

It has been suggested that the Herpes 6 can persist in monocytes / macrophages in a dormant state, although these are not exclusive primary site in vivo latency. The exact mechanism of reactivation of herpes 6 is not clear yet. It has been shown, however, that various types of transactivation can occur between herpes virus 6 and others including CMV, EBV, measles virus and HIV. Is a lymphotropic virus that infects susceptible individuals during the first year of life and generally cause lifelong latency. In a percentage variable, primary infection is followed by an acute illness of short duration, sudden rash. Older individuals may suffer an illness similar to mononucleosis or Kikuchi-Fujimoto disease. It is also capable of causing a wide range of hematopoietic, lymphoid and autoimmune disorders which have been associated with high titers of antibodies to herpes virus 6 and of which the virus has been isolated. These diseases include atypical polyclonal lymphoproliferation of Hogkin disease, chronic fatigue syndrome and systemic lupus erythematosus. General characteristics The herpesvirus 6 virus is ubiquitous in the human population. Infection occurs within the first two years of life; occasionally it is resulting in an acute febrile illness with or without sudden rash. Maternal antibodies are generally present at birth and decline in the first months of life. Seroconversion occurs in most cases between 6 and 18 months and the titles are high in adolescents.

Frequent isolations herpesvirus 6 of saliva suggests that the virus resides and is eliminated from the salivary glands. The viral DNA and antigens were identified in epithelial cells of the salivary glands and from different regions of the upper respiratory tract. So far it is assumed that herpesvirus 6 infection is transmitted by horizontal transmission and there is no evidence of vertical transmission. The most significant property of herpesviruses is their ability to produce a latent infection. During the acute phase of the disease, herpes DNA has been detected in 6 CD4 lymphocytes. During the convalescent phase of exanthem subitum 1. 5 to 2. 5 months after the onset of disease viral DNA is present in a population of adherent cells (monocytes), but not in lymphocytes. It has been suggested that the herpesvirus 6 may persist in monocytes / macrophages in a dormant state, although these are not exclusive primary site in vivo latency. The exact mechanism of reactivation of herpes 6 is not clear yet. Reactivation of the virus seems to occur spontaneously with other herpesviruses in the 5 to 20% of clinically asymptomatic population. It has been shown, however, that various types of transactivation can occur between herpes virus 6 and others including CMV, EBV, measles virus and HIV. clinical data


A variety of clinical disorders have been described as that may be associated with herpes infection 6. Based on current knowledge, which have been insufficient, diseases associated with herpes infection 6 have been classified into 2 groups: diseases caused by herpesvirus 6 infection and disease possibly associated with herpes 6, but without etiologic relationship clearly identified. The first group includes the sudden rash and child-like febrile illness with or without rash, infectious mononucleosis in the absence of heterophile antibodies and cases of Kikuchi disease. The second group consists of certain autoimmune disorders, chronic fatigue syndrome and lymphoid hematopoietic and proliferative diseases. In addition, they have been reported cases of fulminant hepatitis in immunocompromised patients and has been associated with reactivation of herpesvirus 6 and retinitis interstitial pneumonitis. Sudden rash. It is an acute disease that affects mainly small and young adults and is characterized by a short period of high fever (1-5 days) and the appearance of a rash which coincides with the period of defervescence usually occurs in summer and affects both sexes equally. It may be accompanied by sore throat and runny nose. There is absolute neutropenia with lymphocytosis of up to 90% and presence of atypical lymphoid cells with a plasmacytoid cytoplasm. The prognosis is good and does not require treatment. Other febrile illnesses. The virus has been isolated from children with acute febrile disease and otitis and in a percentage of cases the rash may be present. Other symptoms include malaise, irritability, nasal congestion, diarrhea, cough, vomiting.

The picture is benign and does not last more than 4 days. Infectious mononucleosis heterophile absence of Acs. It occurs frequently as a result of reactivation of latent infection by HHV6. The age of patients is the same as those with EBV mononucleosis. It is characterized by an indistinguishable exudative pharyngitis or membranous classical mononucleosis. Lymphadenopathy unlike the MI by the VEB, which tend to resolve in 11 days, may be present to more than 30 days and be associated with hepatosplenomegaly, lymphadenopathy retroperitoneal and blurred vision. Kikuchi disease: This is a histiocytic necrotizing lymphadenitis that has been recently reported. Reported cases come from Japan, Europe, the United States and other parts of Asia. Patients have not painful lymphadenopathy in neck and may or may not be accompanied by sore throat, fever, chills and myalgia. The age of patients ranges between 10and 60 years, with a predominance in 20. Other possible locations of the lymph nodes are axillary, and supraclavicular brachial region. Lymphadenopathy persist for months and can move on to a phase of chronic fibrosis. The prognosis with or without symptomatic treatment is good.

Transplant recipients. Virus reactivation in transplant recipients can lead to interstitial pneumonitis, encephalitis and rejection in some cases. Chronic fatigue syndrome. abruptly starts with a like syndrome accompanied influenza respiratory symptoms and / or gastrointestinal, fever, myalgia, arthralgia, fever, sore throat, unexplained general muscle weakness, excessive fatigue and prolonged postejercicios, neuropsychological symptoms, sleep disorders, among others. These are presented in various combinations, and due to variability among individuals, often the diagnosis of this syndrome is a problem for most doctors. Sjogren’s syndrome. It is an autoimmune disorder characterized by chronic inflammation with infiltration of exocrine glands that can progress to malignant lymphoma. The disease can occur in a primary form, without being associated with connective tissue disease or a secondary form attached artriris rheumatoid, systemic lupus erythematosus or other connective tissue disease. The characteristic and high diagnostic value triad is keratoconjunctivitis, xerostomia and polyarthritis. Any combination of these symptoms can be used for diagnosis. Immunological disturbances consist of functional defects, hyperactivity of B cells and natural killer deficient cells T cells. They can detect a variety of autoantibodies. Systemic lupus erythematosus.

The etiology of this disease is unknown and considered to be a viral infection, altered immune reactivity and genetic predisposition are responsible for the onset of disease. Many infectious agents, they can be imputed to cofactors in disease pathogenesis and herpesviruses are among them. Serological studies have shown high antibody titers against HHV6 in patients with systemic lupus erythematosus. Furthermore they have been detected in biopsy specimens of skin infected with the virus and in primary cultures of peripheral blood lymphocytes of these patients CD4 + / CD38 + was detected the virus genome by in situ hybridization and Acs by immunofluorescence. HHV6 and AIDS. Numerous virus isolates have been conducted in patients with AIDS. Because both viruses share target cell CD4 + lymphocytes, it is suggested that HHV6 is an important step in the progression to AIDS stage cofactor. This virus can cause retinitis in these patients. atypical lymphoproliferative disorders. Among the lymphoproliferative disorders related to infection by herpes virus 6 are: atypical polyclonal lymphoproliferation, non-Hodgkin lymphoma, hemophagocytic syndrome, among others. Finally, some researchers report the discovery of high antibody titers against herpes 6 in patients with myelodysplasia and chronic myeloproliferative syndromes (osteomielofibrosis and chronic myelogenous leukemia). Diagnosis The HHV6 can be isolated from patients with sudden rash during the febrile phase of the disease.

Samples are employed more often peripheral blood monocytes and saliva. These are inoculated on mononuclear cells prestimulated cord phytohemagglutinin. Furthermore, they can be used cell lines as HBS 2, the Sup T1 and Jurtka for variant A virus, and Molt 3 for variant B. The cytopathic effect appears between 5 and 9 days after inoculation the virus and is in rounding of the cells increase in size, merging with multinucleated giant cell formation and vacuolation. The virus can be confirmed by electron microscopy, immunofluorescence and immunoenzymatic assays for detecting antigens and molecular biology methods such as PCR and hybridization enable the detection of viral DNA in samples and in culture. Serological diagnosis is made by ELISA and indirect immunofluorescence using cells infected by the virus lymphoid origin. Epidemiology The herpesvirus 6 virus is ubiquitous in the human population. Is a lymphotropic virus that infects susceptible individuals during the first two years of life and generally cause lifelong latency. In a percentage variable, primary infection is followed by an acute illness of short duration, the sudden rash (children roseola or “sixth disease. ” The older individuals may suffer an illness similar to infectious mononucleosis or Kikuchi disease -Fujimoto. it is also capable of causing a wide range of hematopoietic, lymphoid and autoimmune disorders which have been associated with high titers of antibodies to the herpes virus 6 and of which the virus has been isolated. Maternal antibodies are generally present at birth and decline in the first months of life.

Seroconversion occurs in most cases between 6 and 18 months and the titles are high in adolescents. high titers of antibodies to herpes 6 have been observed in a number of diseases including immunocompromised persons; This suggests that reactivation of latent infection and exogenous reinfection occur with herpesvirus 6. So far it is assumed that herpesvirus 6 infection is transmitted by horizontal transmission through oropharyngeal secretions and there is no evidence of vertical transmission. Treatment Most primary infections do not require specific treatment. In case of related transplant recipients, fulminant hepatitis, hematopoietic disorders, autoimmune diseases lymphoid either the use of some antiviral. The virus is sensitive to foscarnet, ganciclovir and acyclovir relatively resistant.