Serological profile of HSV-2 in Patients attending STI clinic: Evaluation of diagnostic utility of HSV-2 IgM detection 1) Download the resource depends on the source page 2) To download the application, you must be user registered Universia download resource Resource details Membership: Directory of Open Access Journals – Articles Description: Objective: The present study was done to Evaluate the serological profile of herpes simplex virus-2 (HSV-2) Among Patients attending sexually transmitted infections (STI) clinic and to determine the utility of detecting HSV-2 IgM antibodies in Such Patients . A correlation of HSV-2 infection With other STI Including HIV has Also Been Attempted. Materials and Methods: Patients Hundred consecutive Attended WHO STI clinic, with one or more of the complaints as enunciated by WHO in syndromic approach for the diagnosis of STI, Were included as subjects. All subjects Were screened for common STI by standard laboratory Procedures / commercially available kits. HSV-1 and HSV-2 IgM antibody was detected by commercially available enzyme immuno assay kit in all patient’s will. You were will be tested for other STI Also, Namely HIV, Hepatitis B virus, Hepatitis C virus and Treponema pallidum.
Antigen detection was done for Chlamydia trachomatis in genital swabs of all Patients by Bio-Rad Microplate EIA Chlamydia 31189 (United States) kit. Results: Thirty Patients Were found To have genital herpes. In 17/30 (56. 6%) Patients, HSV-2 serology was found to correlate the clinical diagnosis With. The coexistence of other infection in HSV-2 seropositive was detected in 8/30 Patients Patients. None of the Patients Having concomitant infections Were clinically diagnosed accurately. Sensitivity, specificity, positive predictive value and negative predictive value of IgM antibodies for the diagnosis of genital herpes was 73. 91%, 90. 91%, 70. 83% and 92. 91% respectively. Conclusion: HSV-2 IgM detection Could be used only as a test for the diagnosis supportive of genital herpes. It needs to be emphasized That the sensitivity and positive predictive value scores are pointers for further improvement in the commercial assay systems and large sample size to determine the broader May utility of Such systems.
Author (s): Choudhry Shilpee – V Ramachandran – Das Shukla – Bhattacharya S – Mogha Narendra – Id . : 64271508 Language: Inglés – Version: 1. 0 Status: Final Keywords: Co – infection – Resource type: article – Interactivity Type: Expository Interactivity Level: very low Audience: Student – Teacher – Author – Structure: Atomic
Cost: no Copyright: yes : CC BY-NC-SA Technical requirements: Browser: Any – Relationship: [IsBasedOn] Indian Journal of Pathology and Microbiology, Vol 52, Iss 3, pp 353-356 (2009) [References] http://www. ijpmonline. org/article. asp? issn=0377-4929;year=2009;volume=52;issue=3;spage=353;epage=356;aulast=Choudhry [References] https://doaj. org/toc/0377-4929 Contribution Date: Oct 30, 2015
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