German cure for herpes simplex 1 \x26amp; 2? at herpes simplex 1 forum topic 1140303

Hugo It has nothing to do with the conspiracy theories about the big corporations Suppressing a magic cure or the 100 MPG carburetor. No, I have no financial or quid pro quo connection with any pharmaceutical companies. from http://nocureforherpes. com/ “I know this all sounds like a bummer, but it’s the truth, at least for the foreseeable future, in spite of lots and lots of web sites did claim to have a magical” cure “. Those sites exist to make money. Our sites exist to help people deal with the not-so-dreadful reality of living with herpes alongwith about a quarter of the adult population who have genital herpes. Yes, we can talk about oral herpes, too, more Commonly known as cold sores or fever blisters. Almost all the adult population has did virus Eventually, Whether They know It or not. So what’s the deal and why is not there a cure? The problem with the idea of ​​a “herpes cure” is dass die herpesvirus is not a separate entity like a biological bacteria did kann targeted and killed.

It is a little snippet of DNA did Becomes part of the infected cell’s DNA. “Killing” the virus Involves killing the cell. Since the virus very Effectively hides from the immune system inside the cell, there’s not a good way at this time to kill only the affected cell without harming other similar uninfected cells. Further, the infected cells are silent functioning nerve cells and I’m not much in favor of killing off otherwise perfectly good nerve cells. Alright then, so what do we do about herpes? The very best treatments did we have today fall into two basic categories. One is the Nobel Prize winning antiviral drugs Which act to interfere with re-activation of the virus Which results in outbreaks and viral shedding. The other is enabling our immune system to Effectively keep the virus under control so we’re not bothered by it. Immune enhancement, in my opinion, is best Achieved by eating well, getting enough rest, exercise in moderation and active de-stressing. Yes, there are products on the market billed as immune enhancing “supplements”, But They are less well Evaluated for safety and efficacy than pharmaceuticals, so it’s somewhat a caveat emptor situation with regard to potential side effects. ” Tweet


AIDS and its treatment by Chinese Herbal Medicine © 1996 by Gunter R. Neeb In the beginning of the eighties, on patients with severe immune deficiencies a new virus which found by showing did most of prosthesis patients had antibodies against this virus. Nowadays this virus is known in two types, called Human Immunedeficiency Virus Type 1 and 2 (HIV-1 and HIV-2) of Which the first type is more common in the western world. It belongs to a subgroup of the retrovirus-Class, the Lentovirus-Group, Which lead only slowly to disease after infect Their host, seeking Causing a persisiting infection Which remains inactive for a long time. The symptomeless stage may take 10 Years or more, Which to aproximate maximum of 15 years afterwhich most patients show symptoms of mortal immune-deficiency. The virus’ genome besteht of RNA All which is copied to a complementary RNA-string by the enzyme reverse transcriptase. After the first flu-like acute infection in Which a high viral titer can be seen, the virus has killed and infected many CD4 T-Cells and macrophages. The reaction immunic besteht of antibodies, CD-4 and Helpercells -inflammative cells, as well as of cytotoxic CD 8-Cells. After this acute phase the blood is Effectively frred from the virus with a few circulating CD 4-Cells carrying one copy of the inactive genome of the virus. Although the peripheral blood contains no viruses during the inactive phase, the virus itself Reproduces Actively in the lymphatic tissue, brain, and someother regions.

this chronic infection Gradually destroys the CD4 T-Cells I n in a not yet completely Call explained ‘way. After almost all CD-4 T-Cells are destroyed, i. e. if Their count is below 200 per ul, the imunedeficiency stage is reached, and the syndrome is called AIDS. Gradually lymphatic folliculary dendritic cells are damaged leading to a loss of lymphatic follicles and thereafter a complete destruction of the lymphatic tissue. A similar process destroys the thymusstroma. If a new acute infection with HIV-1 or HIV-2 is Suspected or early enough detected, Several antivirus herbs from Chinese Medicine can be prescribed to secure a low infection rate. Since the toxicity of some is very low, They Can be used even as a preventive measure in order to keep the virus from spreading. One promising candidate among them is “zi hua di ding” or viola yedoensis (Pls. Refer to the Following table). Chinese medical herbs Affecting various viruses: List 1 name

Chinese name Effects on Virus / toxicity or LD50 Viola yedoyensis Zi hua di ding HIV / low toxicity arcticum lappa Niu ban zi HIV / low tox. Andrographis paniculata * Chuan xi lian HIV, ECH011 / 13. 4 g / kg Lithospermum rythrorhizon

Zi cao HIV, Jinke, flu, polio, hepatitis / 681. 13mg / kg Altemanthera philoxeroides Lung xin lian zi cao HIV, flu, encephalitis B. retrovirus rabies virus / 455. 5g / kg Lonicera japonica Jin yin hua HIV, flu (PR8), herpes / orphan (mice) 53g / kg Coptis chinensis Huang-lian

HIV, hepatitis B RuS, Newcastle disease / 24. 3mg / kg Epimedium grandiflorum Yin yang huo HIV, polio, ECHO 6. 9, Coxsackie A9, B4, B5 / 36g / kg Woodwardia unigemmata Guo ji zhong guan jue HIV, flu (PR8, Jinke 68-1,57-4, NewA1, Lee, C1232, D), England. II, polio II, Coxsackie, herpes simplex, encephalitis / 1. 7g / kg (mice) Prunella vulgaris Xia ku cao

HIV / low toxicity Senecio scandens Qian li guang HIV / 302. 6g / kg *** Hypericum japonicum Di he cao HIV, hepatitis B / no obvious toxicity Scutellaria baicalensis Huang qin HIV, flu PR8, (Asian A-flu) Xiantai, rhinovirus 17, adenovirus 7 / 3. 081g / kg * Baphicacanthis folium

Da qing ye flu, mumps, encephalitis B / no obvious toxicity Baphicacanthis rhizoma, radix Ban lan gen flu, hepatitis A, B, mumps, herpes encephalitis B. / no obvious toxicity Bupleuri radix Chai hu flu, smallpox / 4. 7g / kg gland (mice) Ledebouriellae radix Fang feng flu, Columbia SK

Polygonum cuspidatum Hu zhang herpes, ECHO9, ECHO11, adenovirus, hepatitis B. , flu, encephalitis B. Coxsackie A, B, polio II / 1363mg / kg * Forsythiae fructus Lian qiao flu (Asian A), nose-17 / 29. 37g / kg (mice) Taraxaci herba Pu gong ying ECHO11, herpes / 156. 3g / kg

* LD50 is given in the doses of chemical scents of the herb. ** LD50 is given in the doses of alcohol extract, IV injection. *** LD50 is given dependent on the herb produced in China; in some countries this herb is very toxic (Geissman, 1964). There are 20 herbs listed in Table 1. The antiviral spectrum and toxicities of each herb are given. Thirteen of them have inhibitory effects on the HIV. Some others have antivirus effects on other viruses. The HIV virus’ ability to avoid immunity response has much in common with some of thesis viruses: The permanent and latent infection is therefore seen in the Epstein-Barr virus and the herpes simplex virus; the antigenic variation by mutations can be found as well in trypanosomes, the influenza virus and Streptococcus some kinds. The induction of an immune-supression shares the HIV virus withsome Staphylococcus kinds and the Mycobacterium leprae. From an allopathic view, it may not be proper to list thesis herbs until theyhave been tested in vivo against the HIV virus; HOWEVER, from a TCM view, if Certain herbs have been proven effective against a Certain virus in clinical trials, the same mechanism may work against another virus in the human body. TCM holds did any herb or drug taken into the body must first affect the body’s metabolism so it can more did Effectively fight the pathogen. Although the concept of an antivirus is an allopathic approach, TCM’s principle of Treating febrile infectious diseases (qing re jie du, heat-clearing and toxin-Eliminating) with herbal remedies can give this approach a new meaning.

The toxicity of thesis herbs is very low, so They Can be used safely for a long period, even over a lifetime, by HIV-infected persons or, as Mentioned before as a preventive measure. The 13 herbs Which Showed inhibitory effects on HIV in vitro may therefore contribute to the treatment of various complications of AIDS. These patients are known to be subject of opportunistic infections and some kinds of cancer. Those are Caused by organisms Which Usually can be controlled Easily by the immune system, like Pneumocystis carinii pneumonia Causing, as well as E. G. Toxoplasma, the Cytomegaly virusand some Mycobacteria like M. tuberculosis and even some normally harmless kinds like M. avium. The functioning of the cellular defese is Necessary for at effective control of microorganisms thesis. Some patients (about 20%) is therefore affected by organisms, Which are Usually controlled by the humoral defense system like Haemophilus influenzae. THEREFORE mostimportant are probably Those herbs Which stimulate the growth of the T-lymphocytes as listed below: Common name asparagus (root)

atractylodes, white (rhizome) Coix (seed) Coriolus (sclerotium) epimedium (leaves) ganoderma (wholesale) lentinus (wholesale) ligustrum (fruit) ginseng (root) phaseolus, white (bean) huang-jing (rhizome) Besides AIDS Patients are liable to develope tumors like the Kaposi’s Syndrome, a slowly developing Usually proliferation of Bloodvessel cells, and to tumors of the B-Cells, the non-Hodgekin-Lymphomes and such of the brain. This might be explainable by a lacking T-cell response against tumor cells or a chronic stimulation of the B cells, another feature of HIV-infections. Since many herbs in Chinese Medicine havebeen proven to stimulate the immune system or some parts of it, thesis herbs can therefore be used in any stage of the HIV infection, i.

e. When An opportunistic infection the occurs or gene rally to stimulate the immune system. Pls. refer to list 2 below: Chinese medical herbs Affecting the immune system (list 2) Promoting lymphoblast transformation Botanical name Angilica sinensis, acutiloba Astragalus membranaceus Atractylodes macrocephala Codonopsis pilosula Coix lachryma-jobi Coriolus versicolor

Epimedium grandiflorum Ganoderma lucidum Gelatin equi asini Ligustrum lucidum Panax ginseng Phaseolus vulgaris Polygonatum sibiricum Polygonum multiflorum Increasing the Number of White Blood Cells Botanical name Acanthopanax senticosus Astragalus membranaceus Cinnamomum cassia

Codonopsis pilosula Comus officinalis Ganoderma lucidum Gelatin Equi asini Ligustrum lucidum Millettia dielsiana Panax ginseng Phaseolus vulgaris Placenta Homines sapientis Psoralea corylifolia Increasing phagocytosis of neutrophilic WBC Botanical Name Common Name Astragalus membranaceus Huangqi (root)

Atractylodes macrocephala atractylodes, white Dioscorea opposita dioscorea (root) Glycyrrhiza uralensis licorice (root) Panax ginseng ginseng (root) Increasing the Number of Mononucleic Macrophages Botanical Name Common Name Coriolus versicolor Coriolus (sclerotium) Glycyrrhiza uralensis licorice (root) Lentinus edodes lentinus (hole) Promoting Phagocytosis of Macrophages Mononucleic Botanical Name Common Name Acanthopanax senticosus ginseng, Siberian (root) Angilica sinensis, acutiloba tang-kuei (root)

Astragalus membranaceus Huangqi (root) Atractylodes macrocephala atractylodes, white (rhizome) Codonopsis pilosula codonopsis (root) Epimedium grandiflorum Epimedium (leaf) Eucommia Eucommia (bark) Ganoderma lucidum ganoderma, lingzhi (wholesale) Lentinus edodes lentinus (wholesale) Panax ginseng ginseng (root) Polyporus umbellatus polyporus (sclerotium) Psoralea Corylifolia psoralea (seed) Rehmannia glutinosa rehmannia (root) II. Herbs Affecting Non-Specific Humoral Immunities

Inducing the Production of Interferon Botanical Name Common Name Astragalus membranaceus astragalus (root) Phaseolus vulgaris (PHA) phaseolus, white (bean) (Ie Astragalus can promote the production of interferon by viral stimulations. ) Anti-Complementary Activities Botanical Name Common Name Cinnamon cassia cinnamon (twigs) Lentinus edodes lentinus (wholesale) (These herbs have triggering effects on the C3 complementary. ) III.

Herbs Affecting Specific humoral Immunities Those Promoting Hypertrophy of antigen-combining Cells in Mice obsessions at the Early Stage of the immuno-reaction Botanical Name Common Name Angilica sinensis tang-kuei (root) Astragalus membranaceus astragalus (root) Coix lachryma-jobi Coix (seed) Comus officinalis cornus (fruit) Those Promoting Hypertrophy of Antibody-Producing Cells Botanical Name Common Name Asparagus cochinchinensis asparagus (root) Coix lachryma-jobi Coix (seed) Coriolus versicolor Coriolus (sclerotium) Epimedium grandiflorum epimedium (leaves)

Ganoderma Lucidum ganoderma (wholesale) Ligustrum lucidum ligustrum (fruit) Ophiopogon japonica Ophiopogon (root) Polygonatum sibiricum huang-jing (rhizome) Polyporus umbellatus polyporus (sclerotium) Psoralea Corylifolia psoralea (seed) Those Suppressing Hypertrophy of Antibody-Producing Cells Botanical Name Common Name Glycyrrhiza uralensis licorice (root) Those Regulating Hypertrophy of Antibody-Producing Cells Botanical Name Common Name Astragalus membranaceus astragalus (root) Those Increasing Antibody Production

Botanical Name Common Name Astragalus membranaceus Huangqi (root) Coriolus versicolor Coriolus (sclerotium) Epimedium grandiflorum epimedium (leaves) Lentinus edodes lentinus (wholesale) Panaxginseng ginseng (root) Placenta hominis sapientis placenta, human Polygonum multiflorum he-shou-wu (wholesale) Rehmannia glutinosa rehmannia (root) Those Suppressing Antibody Production Botanical Name Common Name Angelica sinensis tang-kuei (root) Glycyrrhiza uralensis licorice (root)

Psoralea Corylifolia psoralea (seed) Zizyphus jujuba jujube (seed) IV. Those Herbs Affecting the Production of Different Types of immunoglobulin (Ig) Herbs Which Affect immunoglobulin (Ig) Promotive Suppressive IgG Lentinus edodes Psoralea Corylifolia Astragalus membranaceus IgA placenta hominis Psoralea Corylifolia (Serum) Rehmannia glutinosa IgA Astragalus membranaceus (Secretion) Ganoderma lucidum Polygoni multi floristic

Epimedium grandiflora floristic IgM Astragalus membranaceus Psoralea Corylifolia Coriolus versicolor IgE Astragalus membrananceus Because of the disruption of the immune system, various allergic reactions can be seen in AIDS and HIV (+) patients, most notably hay fever and allergic sinusitis. The Following list contains herbs Which can be used for different types of allergic conditions: List 3: Herbs Affecting Allergic Reactions Herbs Affecting Type I Allergic Reactions Those Suppressing the secretion of histamines Botanical Name Common Name Ganoderma Lucidum ganoderma (sclerotium) Those Providing relief from bronchial spasms due to histamines and Acetylecholine Botanical Name Common Name

Coriolus versicolor Coriolus (sclerotium) Ganoderma Lucidum ganoderma (sclerotium) Epimedium grandiflorum epimedium (leaves) Placenta hominis sapientis placenta, human Psoralea Corylifolia psoralea (seed) Those Providing Relief of Gastrointestinal Smooth Muscle Spasms Caused by Histamine and Acetylecholine Botanical Name Common Name Angelica sinensis tang-kuei (root) Cinnamomi cortex cinnamon (twigs) Comus officinalis cornus (fruit) Glycyrrhiza uralensis licorice (root) Those Which Suppress Allergic Shock or Allergic Skin Reactions Caused by Foreign protein Botanical Name Common Name

Glycyrrhiza uralensis licorice (root) Panax ginseng ginseng (root) Placenta hominis sapientis placenta, human II. Those Affecting Type II Allergic Reactions (Cytolytic) Those Preventing ABO Hemolysis Botanical Name Common Name Glycyrrhiza uralensis licorice (root) Those Increasing the Number of Platelets Botanical Name Common Name Glycyrrhiza uralensis licorice (root) Placenta hominis sapientis placenta, human Rehmannia glutinosa rehmannia (root)

Those Increasing the Number of Red Blood Cells Botanical Name Common Name Acanthopanax senticosus ginseng, Siberian (root) Codonopsis pilosula codonopsis (root) Equi asini equine gelatine Panax ginseng ginseng (root) (These herbs can therefore affect hemolysis. ) III. Those Affecting Type III Allergic Reactions Botanical Name Common Name Astragalus membranaceus astragalus (root) Glyzyrhiza uralensis licorice (root)

Rehmanniae radix rehmannia (root) IV. Those Affecting Type IV Allergic Reaction (Delayed) Botanical Name Common Name Angelica sinensis tang-kuei (root) Bombyx batryticatus silkworm (wholesale) Glycyrrhiza uralentsis licorice (root) As Mentioned above some kinds of cancer can Occur positive in HIV patients. Since there are many herbs in TCM proven effective against various kinds of cancer, only to be listed here excerpt can, since this would exceed this topic by far. So finally in List 4 are listed only herbs Those Which may be effective against cancers in typical AIDS patients, namely leukemia and lymphoma. Since some of thesis autumn are toxic or cytistatic Themselves, They Should not be used Before They are Indicated. List 4: Herbs for cancers in AIDS patients (late stage) Botanical Name Chinese Name

Polysticticum yun zhi Hedyotis diffusa bai hua she she cao Indigo naturalis qing dai Catharanthi rosei chang chun hua Lysimachiaiae Clethroidis zhen zhu cai Botanical Name Chinese Name Camptothecae Acuminatae xi shu Sarcandra glabra zhong jie feng Curcuma aromatica / zedoaria e zhu Brucea javanica ya dan zi Of thesis herbs the first one in the list, Polystipticum is one of the most interesting herbs, since its toxicity is very low, while it is useful for leukemia, lymphoma and liver cancer, by inhibiting the synthesis of the DNA and RNA of tumor cells , Besides this it antagonizes the immunosuppression Caused by cyclophosphamides and cortisone, while Increasing the amount of macrophages, Promotes phagocytosis and Enhances the Board of blastogenesis and rosette forming, seeking being a promising agent for Both enhancing the immune system and Suppressing tumor developement. At the moment clinical western medicine hasnt yet found any solutions exept medicaments like AZT, Which inhibit the function of the reverse transcriptase and THEREFORE have a toxic effect on human cells as well. Some other proposals are searching to find specific inhibitors of the viral protease or the developement of antibodies for the virus surface or synthezising substances Which ought to block the docking of gp120 to the CD4.

But They are quiet far from ready to be used in clinical practice. THEREFORE Traditional Chinese Medicine might Provide some useful alternative by combining herbs with western medicaments or even use them alone in different stages of HIV-Positive patients and other types of immune deficiency syndromes.

Symptoms of HIV in the mouth

11/15/2011 by Diego Oral manifestations of HIV are available in all three symptomatic stages of HIV disease. They are serious when HIV disease progressed to the third stage (symptomatic HIV) and occur during this stage and the fourth stage of HIV disease, AIDS. have symptoms of HIV disease, which appear in the mouth, such as the case with other symptoms, is a number of different causes (bacteria, viruses, fungi) and therefore a number of different treatments Acute HIV infection According to the authors of “HIV infection in Primary Care” by R. Michael Buckley and Stephen J. Gluckman there are a number of oral symptoms of acute HIV infection, including ulcers, sore throat, swelling of the throat and thrush, a fungal infection. Some people experience no symptoms during the acute infection, and some people the symptoms are so mild that they go unnoticed. appear Symptoms of acute HIV infection, generally within two to four weeks after infection and clear up within a month. The most important thing about the symptoms of acute HIV infection is not to forget that they Diracodon; This means that even people seeking medical treatment for these symptoms seek alone will not diagnosed based on symptoms with HIV. Asymptomatic HIV After the acute infection HIV enters an asymptomatic phase.

In this phase, which lasts an average of 10 years, there are no symptoms of HIV, in the mouth or elsewhere. Because of this and the generally mild nature of the symptoms of acute HIV infection the only way HIV status is to be tested to know progress against HIV disease. HIV testing is widely available and easily, and to know the status allows appropriate measures are taken in order and to protect others himself. HIVTest. org helps people find more information about HIV testing and testing centers; See Resources below. Symptomatic HIV A number of symptoms of HIV disease may occur or affect mouth during symptomatic HIV infection, the third stage of the disease. Symptomatic HIV takes between one to three years before AIDS develops, and the symptoms are usually either chronic or recurring. Symptoms that may indicate the mouth or surrounding organs include loud HIV-Symptoms. info shortness of breath and dry cough. The mouth is directly influenced by fungal infections, thrush, a type of oral fungus that causes white plaques and sometimes red patches in the mouth, including by HIV InSite be affected. AIDS While AIDS, the fourth and final stage of HIV disease, a number of infections, viruses, fungi and bacteria, including lead to oral symptoms.

This can cause lesions or blisters, and in some cases lead to damage or destruction of oral tissues. Besides thrush other fungi caused oral symptoms AIDS histoplasmosis and Cryptococcus neoformans. Both lead to ulcerations in the mouth; Histoplasmosis on muscosal tissue and Cryptococcus neoformans on the hard palate, after HIV InSite. Among the causes virus symptoms AIDS are herpes viruses, including cold sores, which can be difficult especially in people with weakened immune systems. Another possibility is the oral participation of Herpes Zoster or shingles, causing pain and rash with blisters and which affect the mouth or nearby areas of the face. Cytomegalovirus, another herpes virus, can cause necrotic lesions in the mouth after HIV InSite. Human herpesvirus-4, also known as Epstein-Barr, may be oral hairy leukoplakia, lead white lesions appear, Be hairy and found that along the mucosal tissue. Human papillomaviruses (HPV) cause oral lesions in AIDS. Bacterial infections in the mouth while AIDS can necrotizing ulcerative periodontitis (NUP) and linear cause gingival erythema (LGE). After HIV InSite both can result in loss of soft tissue and bone in the mouth, lead a person regardless of the state of oral hygiene. Cancer can occur in the mouth during AIDS, including Kaposi’s sarcoma and lymphoma. Kaposi’s sarcoma results in lesions that generally purple, but can also blue or red; by HIV InSite they may ulcerate or infected. Lymphoma in the mouth appears as a painless swelling, after HIV InSite, ulcerate can.

treatment Treatment for oral conditions associated with HIV disease varies depending on the specific root of the problem. Many conditions respond favorably to treatment with antiretroviral drugs, the treatment of HIV disease generally used. Others, however, must be precisely aligned with agents such as antibacterial, antiviral, antifungal and antiparasitic drugs. The treatment of any oral manifestation of HIV must be determined in conjunction with a health care professional to ensure that it does not lead effectively and adverse interactions with other medications. Related

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. . All or many CNS diseases are due to . . . ergo do Must do something in Frühststadium that the BAYER propagated not stolen, they are anyway . . . ! ! For 10 years I am working on a NANO-HYDRO-gel that meets these requirements, no drug is and on top ORIGIN has here can be so accessible even in the toughest times in the active complexes (see all, ALL, “viral infections, MUSHROOM infections “) AVIZENNA:

The dose makes the poison ! AND The compound of URALT KNOWLEDGE with HIGH-TECH’s our only chance, I could do that well on TUMOR DISEASES relate but I think I should leave it, because the unbelieving eyes and the shaking of the head I see now . . . ! ? Where are the STUDIES . . . ? ? I was years in the pharmaceutical industry .

. . I trust only the STUDIES, which I myself falsifying . . . someone has said before me . . . ! ! But what I want here to address with this TOPIC? HERPES and MUSHROOMS only spread and very fast, very fast when the IMMUNE SYSTEM is damaged . .

. Who is the biggest with 1000% distance stressor, as well for the CNS ? ? The PHYSICAL STRESSORS, HAARP which DIGITISATION the living conditions and the perverted “substituted technologies” . . . . all with the AIM to damage the central nervous system . . . ! ! !

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http://techseite. wordpress. com/ , Genital herpes: Pritelivir reduced Viral Shedding Seattle – The release of virus (viral shedding), which occurs at genital herpes disease in the asymptomatic stage, was in a randomized trial in the New England Journal of Medicine (2014; 370: 201-210) by Pritelivir, the first of a new drug class are significantly suppressed by helicase primase inhibitors. The number of days with herpes symptoms was reduced. Doubts about the safety of the drug, resulting from animal experimental results, but so far could not be dispelled. Herpes infections can be treated with DNA polymerase inhibitors for three decades. The three currently available drugs acyclovir, valacyclovir and famciclovir often relieve symptoms, but they can not stop the virus excretion through the mucous membranes (Viral shedding). In addition, there may be resistance in a long-term therapy. Therefore, there is need for further drugs which have a different mechanism of action in order to avoid cross-resistance and reliable protection against a transfer. The company AiCuris from Wuppertal, an offshoot of Bayer HealthCare has tested a completely new drug.

Pritelivir is an inhibitor of a complex of the two enzymes helicase and primase. This viral enzymes separate the DNA duplexes, which is a prerequisite for the growth of the herpes virus, which is known to anchor their genes in the human genome. Pritelivir engages at an earlier point of virus replication as a DNA polymerase inhibitors. Also must Pritelivir be different than acyclovir, valacyclovir or famciclovir not activated by phosphorylation. Through the different mechanism of action for cross-resistance are also unlikely. Following the successful completion of in vitro experiments and animal studies Pritelivir was tested at seven centers in the US to 125 patients in four different doses. An additional 30 patients were treated with placebo. All participants suffered at least 12 months from recurrent genital herpes infections, but were free of symptoms at baseline. The primary endpoint was the genital viral shedding. It was by quantitative polymerase chain reaction (PCR) carried out in a day carried out by the volunteers genital swabs. How to tell Anna Wald of the University of Washington in Seattle and co-workers now, lowered the Pritelivir Viral shedding during the 28-day treatment at the dose of 75 mg / day. 87 percent The herpes viruses were detected by PCR only 2. 1 percent of the days in the smears against a share of 16.

6 percent in the placebo arm. The percentage of days with genital lesions was also reduced from 9. 0 to 1. 2 percent. The differences from placebo were highly significant in all endpoints. It was also – even at the low doses of Pritelivir – no evidence found on a resistance (which, however, after a short treatment time, and a small number of participants of the study, only a small influence has). The tolerability of the drug was good: Only three patients discontinued the study. The most common side effect could be a nausea. In an animal study, however inexplicable dermal and hematological findings were encountered. The US Drug Administration FDA has therefore come to a halt the clinical development of Pritelivir in May, 2013. Whether it can be resumed after clarification of the study results, it is currently unclear. http://www. aerzteblatt.

de/nachrichten/57257 The BLOG is not finished, all documents and technical articles are still missing, because I am angwiesen on supporting the reader READER, do not blindly go in the PHARMA LOBBY, but with ALTERNATIVE including . . . . sicher in combination: ANCIENT KNOWLEDGE \x26amp; HIGH-TECH the “SCHOOL SCIENCE”, which is 99% Pharma Hörig far superior ! ! LG, the creation obliged “ET” etech-48@gmx. de egon tech End of guest contribution , .

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