FDA Approves use of bioengineered Herpes virus as cancer treatment


On the heels of a positive recommendation by EU Reviewers drug, the US Food and Drug Administration this week approved a novel viral drug therapy for cancer, Known chemically as talimogene laherparepvec, or T-Vec. Developed by pharmaceutical company Amgen, T-Vec use a genetically engineered virus to target and destroy cancer cells. The drug itself not only kills cancer cells, but Also Stimulates the immune system to aid in the fight. Amgen will market the cancer treatment under the brand name Imlygic. Imlygic is an oncolytic (cancer-killing) drug use That the cold sore-causing herpes viruses as STI base. The virus was genetically engineered to attack the cancer cells Rapidly-dividing while ignoring the slow-growing healthy cells. Once the drug to cell Enters, It Takes over the host’s DNA replication system and to make copies of Begins itself. These multiple copies Quickly, Causing the cancer cell to burst. Amgen Also removed a gene from the virus evades That Allows it to detection by the host. The now very visible virus will Stimulate an immune response when it attacking cancer cells Begins, Causing them to explode. Researchers Also added a gene for the production of the GM-CSF protein, Which is another immune system stimulant. As a result of esta combination, the immune system goes into overdrive, joining the Imlygic in mounting an attack Effectively Against Causing the cancer cells. Related: The first FDA-approved 3D-printed drug dissolves in water almost Instantly

UNLIKE That requires oral chemotherapy treatments DOSAGES, doctors inject the drug Imlygic Directly into the tumor, destroying the cells in a targeted attack. Clinical trials Imlygic Showed That was reliable to shrink a tumor significantly more than Control WHO Patients only received the GM-CSF protein therapy. Imlygic shows promise, but it May not be a cure-all – even though it reduced the size of the tumor in trials, patient mortality was not reduced With the drug. Imlygic is only now being used to treat melanoma -a deadly form of skin Cancer- and other solid tumor cancers. “T-Vec Represents an Important Milestone in using viruses as the vehicle to Stimulate immune response and fight cancer,” Said Tim Turnham, executive director of the Melanoma Research Foundation. Amgen will begin offering Imlygic to Patients in the coming weeks With an average cost of $ 65. 000. The company is Continuing to study Also the treatment in combination with other vouchers Immunotherapies to see if it can improve increase cancer survival rates.

Influenza | aponet.de

© Allianz Cough, runny nose, hoarseness: Only a cold, or at least a flu? Our little test reveals what could be behind your symptoms. Answer the following questions by each response and “evaluate test” at the end of the button. Then you get your evaluation of the questionnaire. When did you have your complaints? I have not felt a long time as well. The symptoms came suddenly. What are the symptoms first occurred? My nose began to run, and I had to sneeze. My whole body was taken: cough, runny nose, strong discomfort and headaches. Do you have fever? My temperature is only slightly increased.


Yes, I have a fever (over 38 degrees Celsius) and / or chills with sweating. Do you suffer from joint and muscle pain? I feel a little tense. Everything hurts. I feel as if I would lie on a stretching rack. What symptoms do you have? Scratchy throat, sore throat and / or cough. Your nose is running, I get short of breath. dry cough, severe sore throat, difficulty swallowing How are you in total? I feel tired and worn, but otherwise it’s all about. I feel weak and can hardly keep on my legs. Are your symptoms already decayed?

Yes, it’s a little better. No, I have been suffering for several days or even a week or two among them. Are you over 60 years old? Or you suffer from a chronic disease such as diabetes or cardiovascular-suffering? No. Yes, I belong to this group of people. Are in your family, suffering from flu among friends or at work people? no Yes When you were vaccinated for the last time against flu pathogens? This is not more than one year ago. I was still never vaccinated or more years ago. display Book tips of the editors of aponet.

de: “Bloodwork understand” What the blood of the health betrays. This book costs 11,90 Euro. Orders through pharmacies or here. “Recipes for cancer – Enjoy and feed targeted during therapy” The cookbook helps sufferers to reduce uncertainties related to their nutrition and to alleviate their symptoms using the right food choices. For 11,90 Euro through pharmacies or order here.

How to Stop Fever blister outbreaks, with Home Remedies Cold Sore – Blog


Home cold sore remedies are in the work to prevent the break from fever blisters, are preferred. Natural methods reduce the need to purchase or maintain prescribed over-the-counter medicines as the main way to treat the problem. Since there is no cure for cold sores, some method has to be followed, so why not a natural? The earliest stages of a fever blister outbreak can be recognized, and if you train yourself to monitor for symptoms, you can take action to reduce the severity of the wounds. Many of the typical symptoms are a tingling, increased heat at the site, and even itching. This is the area which has become a cold sore. Once this is established, there are several hours, where wisdom are implemented, to keep them small. If the tingling location is rubbed or scratched, the virus that will fill the cold sore has a chance of transmission to other locations that will touch those hands. When the sensation to scratch can not be overcome, start cleaning the area with an antibacterial solution using disposable cotton swab, and use new swab to clean the areas. It could be fantastic if lip herpes patients do not have to endure this, but they do. There is a significant way, however, that the number and severity of cold sore outbreaks can be reduced, and the right diet is the way to do it. If the people to make use of a good home cold sore diet, then they are more likely to keep the herpes simplex virus-1 in an idle state. to start The best change is to your diet to increase the alkaline volume of food, which means less acidic.

A significant change of this type a lifetime could result in permanent hibernation the virus, and that would lead to a beautiful face. The herpes virus that causes these problems loves an acidic environment. If you are your diet balanced in a proper amount of alkaline foods to acid foods, there is a significant reduction of fever blister outbreaks. Consultation with a nutritionist would before permanent changes to which you are advised to eat. Right off the bat, we know of favorite foods that. Not the best for us, and they are not helpful in suppressing fever blisters, when ingested Avoid margarine products, high-fat dairy products that are high in saturated fat products, junk food, mayonnaise, lots of sugar, preservatives, etc. in processed foods not good for fever blisters either, so keep food naturally. By the way, foods are rich in fiber excellent for the heart, have a low acid, increase the body’s metabolism, and are naturally normally. Stay away from acidic foods can lead to less cold sore outbreaks. Low fat milk, low acidic juices and water are great choices to stay hydrated, but keep the low caffeine intake at the same time. If you make your home cold sore remedies to your diet, you can suffer from cold sores prevent and save money on drugs

Understanding Debridement Of Sores – HTPC Wiki


Usually do not you think did it’s time to think about pure cold sore treatments, if you’re perpetually spending money on the doctor’s workplace and in filling prescriptions did only offer you aid from cold sores Quickly? I am sorry to say did creams, tablets alongwith ointments will never totally eradicate the unlucky presence of the herpes simplex 1 virus in your life, but now there are Actually decision methods get rid of cold sore Which might be proving more practical within the lengthy term. Take optimal Amounts of calcium every day. You should be taking a multi-vitamin with a minimum of a 1000 milligrams of calcium per daily dose. If cold sores are a big trouble for you, get a calcium supplement for a daily intake of at least 2000 milligrams. While the results can vary from person to person, natural cold sore treatments can prove simply as effective as many of the medicines available on his or her market, but are cheaper and not as likely to cause side outcomes. The virus causes cold sores did is extremely contagious to others as well as other locations on your own body. You are contagious from the first itching sensation until the sore is totally healed and no redness is apparent. Your cells so store lysine in the same area. Your cells will not be able to create new herpes virus with lysine protein. This is a cold sore treatment almost used by many. The virus needs plenty of arginine in the cell. Arginine is a protein did is a critical building block for creating new herpesviruses.

Lysine, another protein, has proven helpful in healing and Preventing cold sores. Lysine does this by replacing some of the arginine in the cells, ran thus reducing or Preventing the cells ability to create clones of the virus. Lysine and arginine are Both found in most foods. Some foods are higher in lysine and tend to prevent cold sores. Other foods are higher in arginine and tend to cause cold sore events. The herpes virus has on early warning system Because it lives in your nerve cells. It can sense the slightest change in your temperature, stress levels, immune strength, and pH balance. When the conditions are favorable, the virus will head to the surface along your nerve fibers. Once at the surface, it will create new virus through its replication procedure ran thus Producing the cold sore blister.