By Fabian Dupont © olly – Fotolia Glandular fever, also mononucleosis (infectious mononucleosis) called, is a common, often harmless, viral disease. Almost all people over 30 carry the virus. Since infectious mononucleosis is transmitted primarily via the saliva, called glandular fever also kiss disease, in English: kissing disease. Here you can read everything about glandular fever. Glandular fever: Contents Glandular fever: Description The glandular fever is caused by the Epstein Barr Virus (EBV). Since most teenagers and young adults are affected by the symptoms in industrialized nations, known in the vernacular glandular fever also students or students fever disease. In England, the disease is often called “kissing disease” as the virus is mainly transmitted by kissing. Especially “kiss active” population, for example, students are, therefore, concerned increased. EBV is transmitted through body fluids.
Particularly high is the viral load in saliva, so it will be passed quickly in intimate contact. Other routes of infection are also conceivable, however, make an exception. Also available on other mucous membranes than the oral mucosa and the blood can detect the virus, therefore may exist in blood transfusions or during sexual intercourse, a contagion. The Ebstein Barr virus infects and multiplies in a subset of white blood cells, lymphocytes, and in mucous cells in the throat. These are the only cells in the body, in which the virus can penetrate. Between infection and outbreak of the disease are usually four to six weeks. Who knows about his infection, should avoid giving the virus to others for several weeks (kissing disease) . because the virus via saliva sharing is possible even long after resolution of symptoms. A person who has been infected with the EB virus remains a lifetime carriers of the virus. The immune system keeps the pathogen but in chess, you will therefore not fall ill again normally. back to contents Additional information for you Video Playlist: glandular fever
Glandular fever – what helps? Here is how to reduce fever and what helps in severe cases. More Videos about glandular fever: 02:59 min Glandular fever – what helps? 02:56 min How to Measure Fever 02:11 min Glandular fever – Precautions 03:09 min Glandular fever – signs Glandular fever: infection Everything important to the typical infection because of mononucleosis read the post glandular fever – infection.
back to contents Additional information for you Glandular fever: symptoms Everything important to the typical signs of mononucleosis read the post glandular fever – symptoms. back to contents Glandular fever: Causes and Risk Factors The glandular fever is caused by a virus. This virus is one of eight dangerous for the human herpesviruses. Each of them triggers a different disease, are some examples of lip / genital herpes or chickenpox and shingles. Causative agent of mononucleosis is called, named after its discoverers Ebstein-Barr virus. This can only cause glandular fever, but not, for example, cold sores. When EB virus is a DNA virus that can be found in very many people. The virus can survive and propagate only in certain white blood cells (B lymphocytes), as well as in certain mucosal cells of the pharynx.
is transmitting the infectious mononucleosis via saliva. In children this is often done by family members or, for example, in kindergarten through common toys, as young adults almost exclusively through kissing. The virus can not survive for long outside the human and always need the human host in order to multiply. In order for a transfer to take place, must be held close contact between an uninfected and an infected person. Anyone who has been infected with the Epstein Barr virus is lifelong carriers of the virus. The risk of re-infection is therefore only for people who have never been infected by EBV. Glandular fever: alcohol and drugs pollute the liver The infection also burdened the liver often considerable. Therefore sufferers should try when mononucleosis to avoid alcohol, so as not to damage the liver even further. Because many drugs are degraded in the liver, some drugs for the duration of the disease damaging substances must be replaced by less liver. In some cases, the liver for months remain elevated, so regular blood tests are required, and the consumption of alcohol should be set for several months. Glandular fever: Sport with caution! Whether Pfeiffer’s glandular fever impossible Sport, also depends on the course of disease.
In the acute phase, or in severe infections should avoid sports affected very, later a very light movement training is often possible. Because of the mononucleosis often greatly swollen spleen is under intense stress or by force from the outside also the risk of a crack of the strong by bleeding organ. The case caused bleeding can be life-threatening. Therefore, contact and combat sports are prohibited during this period. That glandular fever first appears during pregnancy, is extremely rare. For most women of childbearing age carry the Epstein-Barr virus already in and have built up a body’s own protection. One assumes that an EBV primary infection may increase the risk of preterm delivery, or much less frequently a malformation during pregnancy. back to contents Glandular fever: research and diagnostics Glandular fever is often not or only detected late because the main symptoms such as sore throat, fever and swollen lymph nodes also occur with simple flu-like infections colds. Doctors refer to symptoms that can be caused by other diseases as “non-specific”. It means that he must always think when they occur and to a host of other diseases. Only if the fever does not decrease, or the patient complains for weeks about fatigue, revealing a blood test may one standing behind it glandular fever.
Most glandular fever occurs in people under 30 years, and often can then connect to an infected partner prepared. In the blood, there are following typical changes :. The white blood cells and the concentration of liver enzymes are elevated, and there can be specific antibodies against the EBV prove. These antibodies are substances of the immune system, which fit exactly on this type of virus. They are the proof that the body tries to defend itself against these pathogens. In rarer cases come to visible symptoms such as rash, yellowing of the skin (jaundice), or an enlarged spleen, which can palpate externally even. Because of strep throat often occurring and typical blood disorders older textbooks and articles often speak of a so-called Monocytic synonymous with glandular fever. This term is now outdated. We now know that the proliferation of white blood cells does not come through a propagation of the monocytes into being, but that it is in the defense cells to lymphocytes, which are due to the rapid formation somewhat deformed. For this reason it is also called Pfeiffer cells or atypical lymphocytes. back to contents Additional information for you Glandular fever: Treatment
As the glandular fever is treated, see the contribution glandular fever – treatment. back to contents Glandular fever: clinical course and prognosis While the glandular fever in children runs often without symptoms, however, it is usually in childhood to primary infection. Especially in countries with lower (hygienic) standard of living, such as in Africa or South America are virtually all infants already with the mononucleosis virus (EBV) infection. Although it rarely comes to symptoms in young children, it is believed that due to the EBV infection, the risk for some blood cancers (for example, B-cell lymphoma, Burkitt’s lymphoma, Hodgkin’s disease) increases. In very rare cases, the glandular fever is chronic. That is, the symptoms persist for months or even years. This rare history is however observed mainly in Asia and is very unusual for Europeans. Problems with the direct symptoms of glandular fever are more common in industrialized nations, as occurs here the infection on average at a much later stage of life. The disease is then often difficult. As a rule, glandular fever proceeds without complications and the need for any special treatment. However, there is suspicion of a complication, or when blood values deteriorate particularly strong, patients are often treated for monitoring in the hospital.
Most heals from a glandular fever without permanent sequelae. Only very rarely causes glandular fever and its complications cause permanent damage. back to contents Was this page helpful to you? Thanks for your review. Read more about glandular fever Page of 4 Date: 19:02:14 resources / editors Author: Fabian Dupont Template: Dr. med.
Beate Eigler Sources: Duale Reihe – Internal Medicine, Thieme-Verlag, 3rd edition (2013) W. Pieper, Internal Medicine, Springer-Verlag, 2nd edition (2013) Duale Reihe, Microbiology; Thieme-Verlag 4th Edition Dual row- Pädiatre, Thieme-Verlag 4th edition (2012) Speer, pediatrics, Springer-Verlag, 4th edition (2012) W. Rath, disease during pregnancy, Thieme-Verlag (2005) V. Briese, diseases in pregnancy: Manual of Diagnosis A-Z, De Gruyter (2010) DEGAM GUIDELINE NECK PAIN: 12/10/2013: http://www.
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com/health/mononucleosis/DS00352/DSECTION=treatments-and-drugs Michigan university med school. 10:12:13 http://www. med. umich. edu/digitallab/m2pathlabs/hemepath/PDF%20files/2004%20concise%20review%20mononucleosis. pdf New England journal of Medicine: 10:12:13 http://nuhem. com/emlinks/LLSA%20Articles%202012/Infectious%20Mononucleosis. pdf PubMed: EBV in the SS: Polling 28/12/2013 http://www. ncbi. nlm.
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