Files veterinary medicine – Rhodococcus equi pneumonia and colitis in a foal: First report in

First case described in Chile of pneumonia and colitis Rhodococcus equi in a potrillo Rhodococcus equi pneumonia and colitis in a foal: First report in Chile E. Paredes1, M. V. , Dr. med. vet . ; R. GALLEGO2, M. V .

; A. M. Channel3, M. V. , M. Sc . ; O. ARAYA4, M. V. , Ph. D . ; E.

CHAHUÁN5, T. M . ; P. THOMAS5, T. M . ; J. ZAMORA5, M. V. 1Institute of Animal Pathology, Fac. Veterinary Science, Universidad Austral de Chile. Military 2Criadero Riñihue, Chilean Army. Animal 3Patología. Fac.

Of Agriculture and Veterinary. Universidad Nacional del Litoral, P. Kreder 2805, 3080 Esperanza, Santa Fe, Argentina. 4Instituto of Veterinary Clinical Sciences, Fac. Veterinary Science. 5Instituto of Microbiology, Faculty of Sciences, Universidad Austral de Chile. ; Casilla 567, Valdivia, Chile. SUMMARY Rhodococcus equi was isolated for the first time in Chile from lung sample, bronchial lymph node and mesenteric lymph node Obtained from a 3 month chronic enteritis and foal With pneumonia. Gross lesions Were Characterised by pneumonia pyogranulomatous multiple abscesses varying size. Multiple well-defined necrotic foci, 1 to 3 cm in diameter, in the mucosal surface Were of the colon, and mesenteric lymph nodes Were enlarged. Due to the infectious disease condition, it is Necessary to carry out further studies to determine STI epidemiological relevance in Chile.

Keywords: pneumonia, colitis, Rhodococcus equi foal. Key Words: pneumonia, enterocolitis, Rhodococcus equi foal. INTRODUCTION Rhodococcus equi (R. equi), formerly classified in the genus Corynebacterium as C. equi, is an important pathogen of foals being pyogranulomatous etiologic agent of bronchiolitis and ulcerative enteritis, preferably less than 6 months old young horses (Burks, 1996; Nay, 1996; Fernandez, 1997; Castagna Vargas, 1998) with abscess formation of thoracic and mesenteric lymph nodes (Knottenbelt, 1993; Lopez 1995; Van Kruiningen, 1995) also may occur joint injuries, skin, bone , eye and various viscera (Fernandez et al. , 1995; Van Kruiningen, 1995; Burks, 1996; Nay 1996). R. equi has also been isolated from healthy and diseased animals of other species, such as pigs, cattle, sheep and also in free-living animals (Bern and Lämmler, 1994; Soedarmanto et al, 1997, 1998. ). In man is gaining importance as an emerging disease, particularly in immunosuppressed individuals (Prescott, 1991; Bern and Lämmler, 1994; Fernandez et al. , 1995; Takai et al. , 1995; and Lämmler Fuhrmann, 1997).

This article aims to communicate the first isolation in the country of R. equi, describe the typical injuries and cultural characteristics and antibiotic sensitivity of germ found in a dead foal pneumonia in the Tenth Region, Chile. MATERIAL AND METHOD In a stud farm 10 cases of diarrhea as the only symptom in foals of different breeds of 20-45 days old were detected in mid-November 1995, which did not respond to therapy potentiated sulfa (sulfa + trimethoprim) for 5 days and supportive therapy (oral rehydration salts, ringer lactate serum EV, bismuth subnitrate Flumixin oral Meglumine, EV); due to inclement weather, the offspring had remained confined stabling night with their mothers in a shed for three days, without spare bed. At the end of November totaled 40 cases detected (80% of total offspring), when Salmonella sp is isolated. E. coli and from faecal samples, starting specific treatment according to antibiogram sensitivity (Advocin® and Baytril) for 4 days, with no clinical improvement in most of them. In January 1996, 14 offspring remain with diarrhea (35% of affected), 9 of which had also respiratory compromise, which were treated with gentamicin and sodium penicillin E. V. (3 times a day for 10 days), with no remission of the symptoms. It was decided to leave without antibiotic treatment to a colt race Selle Français, 90 days old, being sacrificed later. necropsy according to the technique described by Walls and Cubillos (1995) was performed, taking samples in neutral formalin 10% of affected tissues (lungs and large colon) and samples of lung, lymph node bronchial and mesenteric lymph node for microbiological examinations. To this effect it was plated on sheep blood agar and chocolate agar, later to make morphological, physiological and biochemical isolates according to described by Holt et al exam.

(1994) and Fuhrmann and Lämmler (1997). In addition, isolates were determined sensitivity to different antibiotics by conventional methods. RESULTS AND DISCUSSION a) Clinical manifestations and laboratory tests. The clinical symptomatology was characterized by watery diarrhea began at 36 days of age, with no initial respiratory compromise or alteration of physiological constants situation is described by Yager (1987) and Burks (1996), who argue that infection R . equi, diarrhea this may be the only sign. At 75 days of age, respiratory symptoms (mild cough, crackles and hissing noises cranioventral level of both lungs) and fever, similar to that described by Prescott (1991), Vivrette (1992) and Burks (1996) are detected. During the course of the disease he continued suckling foal. After initiation of respiratory symptoms blood count was performed, finding neutrofilia (10. 0 mil / microliter) with deviation to the left (N. baciliform 1. 5 mil / ul) and increased plasma fibrinogen concentration 10 g / l). The insidious presentation of the disease in this colt, characterized first by diarrhea and later by bronchopneumonia tending to chronicity and the history of other respiratory symptoms sporadically presented earlier in the stud farm, became suspicious of R.

equi infection , since the clinical characteristics coincided fully with those described in the literature (Vivrette, 1992; Knottenbelt. , 1993; Fernandez et al, 1995; Lopez, 1995; Van Kruiningen, 1995, Burks, 1996; Nay, 1996; Fernandez et al . , 1997; Vargas Castagna, 1998). b) Findings anatomical and histopathological. Necropsy performed the animal accentuated suspicion, since the postmortem examination revealed that serious injuries were confined to lungs and large colon. Both lungs were observed without collapsing, irregularly firm, with the presence of multiple nodules of varying sizes scattered all lobes and protuían into the pleural surface. When cutting the lung tissue, these nodules were observed as multiple focal and confluent areas of yellowish white color, completely replacing the lung tissue (Figure 1) and corresponding to areas of chronic inflammation, central necrosis and discrete purulent exudate. Bronchial lymph nodes were enlarged, hyperemic and exudative. Figure 1. Lung (cutting surface): confluent foci of necrosis and purulent inflammatory reaction. Lung (cut surface): large and confluent granulomas caseated. In addition, the lining of the colon showed greater number of circular ulcers, up to 3 cm in diameter, with a thick border of cream and a depressed with traces of necrotic tissue (Figure 2) center. Mesenteric lymph nodes were increased volume and had a cutting surface with great whitish exudates.

Figure 2. greater Colon: Circular mucosal ulcerations. Mucosal surface of the colon: well defined necrotic foci. Furthermore, histopathology found in the lungs the presence of large areas of necrosis with severe inflammatory reaction neutrohistiocitaria type, finding some giant cells. In turn, the more severe inflammatory bowel exhibited neutrohistiocitaria reaction type with large areas of necrosis, covering mucosa and submucosa. c) Microbiology. All lesions observed, and that characterize a disorder caused by this bacterium box, were confirmed with isolation lung, bronchial lymph nodes and mesenteric pure culture of a Gram positive bacteria and weakly acid resistant Ziehl – Neelsen modified, pleomorphic aspect cocoide (0,71,4 microns), distributed in cuneiform palisades or encapsulated. Colonies were small, 2 to 3 mm in diameter, smooth, shiny, pale mucous salmon acquired after March 4 days of culture and development in gelatin presented a strong orange. Other features are included in Table 1. TABLE 1. biochemical and physiological characteristics of R. equi strains isolated. Biochemical and physiological properties of the isolated strains.

biochemical and physiological characteristics Motility catalase gelatinase lipase urease Nitrate reduction CAMP Glucose acid Acid Lactose Acid Mannitol – +

– + + + + – – – According to the stated characteristics, it was identified as Rhodococcus equi strain, being sensitive to different antibiotics that are included in Table 2. TABLE 2. Antibiograms of the R. equi isolates. Antibiogram of the isolated R.

equi strains. Antibiotic Sensitivity Penicilinaaa Cloxacilinaa Erythromycin Lincospectin Bipencilaaa Baytrilaaaa Advocinaaa Ceftiofuraaa Resistant Resistant

Sensitive Sensitive Sensitive Sensitive Sensitive Sensitive Although considered to R. equi has a cosmopolitan distribution, they had not described in Chile infections in foals by this agent. The table causes this microorganism is generally sporadic in enzootic areas, but also outbreaks have been reported responsible for great economic losses in the stud farm, although the most common is that the infection goes unnoticed (Knottenbelt, 1993, Burks, 1996; Soedarmanto , 1998). R. equi, causing a suppurative bronchopneumonia Subacute to chronic, associated with purulent lymphadenitis, pneumonic infections that 50% are complicated by intestinal infection (Yager, 1987), especially in foals under 6 months of age and particularly those of January 3 months of life, in which it has not yet fully matured their immune system being immunocompromised adults also particularly susceptible to infection (Burks, 1996). You can not ignore that, in addition, on some occasions it is believed that viral infections may be predisposing factors, such as with equine herpesvirus type 2 (EHV-2) (Nordengrahn et al. , 1996).

Treatment of the disease is difficult, not by the resistance R. equi may have antibacterial, but rather the facultative intracellular bacteria property, a factor that probably concurred in failure of therapy instituted in previous cases, since the isolated strain was sensitive to several antibiotics (table 2), including employees at the farm, although it must be remembered that in vitro conditions are different from those in vivo, which does not allow the conclusion that the antimicrobial susceptibility test result can be the same in the animal. Also, it should be recalled that the organism quickly becomes resistant when the antibiotic is used alone, hence it is necessary to use simultaneously more than one drug in prolonged, being recommended the primary application of erythromycin and rifampin, reinforced therapy support such as dimethylsulfoxide, aminophylline and even ranitidine (Fernandez et al. , 1995; Burks, 1996). However, Gustafsson et al. (1997) report that erythromycin may induce severe colitis in horses associated with large changes in intestinal microbiota of these animals. The discovery of R. equi in the country to presume that the infection is quite widespread, causing serious problems, given the survival and development of the agent in the external environment (especially where there is overcrowding, agglomeration of fecal material and dusty environments), the different routes of transmission, the difficulty of achieving an early diagnosis by the characteristic insidious disease development and the progressive increase in the incidence denouncing the literature, are a set of attributes that make R. equi one of the most problematic pathogens, refractory to treatment and causes a high rate of mortality in foals (Higuchi et al. , 1998). It is therefore high convenience continue studies on the subject to determine the epidemiological importance in the country, not only for its role in the health of the horses, but also because it is considered an important agent of emerging infections the human species, especially in immunosuppressed people. SUMMARY Described for the first time in the country, isolation of Rhodococcus equi from an infection in a colt of 3 months old, who suffered from chronic enteritis and pneumonia.

Also, they disclosed the lesions observed in the postmortem and histopathological examination consisting of multiple pulmonary nodules with areas of chronic inflammation, central necrosis with purulent exudate and bronchial lymph nodes increased in size: hyperaemic and exudative. In addition, the large colon showed ulcerations with necrotic tissue and mesenteric lymph nodes were enlarged with great exudation, lesions which show typical features that characterize this pyogranulomatous infection of foals. As this is an emerging infectious disease, it is necessary to continue studies, in order to determine its epidemiological relevance in Chile. _________________________________ Accepted: 05/02/2000. BIBLIOGRAPHY BERN, D. , CH. Lämmler. 1994. Biochemical and serological Characteristics of Rhodococcus equi isolates from animals and humans. J. Vet.

B Med. 41: 161165. [Links] Burks, B. 1996. Managing Rhodococcus equi infections in foals. Vet. Med. 91: 656662. [Links] CASTAGNA VARGAS, A. 1998. Infecçâo Rhodococcus equi.

Quoted in RIET-CORREA, F. , A. L. Schild, M. C. MENDEZ (Eds. ). Doenças of ruminants and equines. Edit. University, Pelotas, Brazil. [Links] FERNÁNDEZ, A. S.

, S. M. Estein, P. SOTO. 1995. Rhodococcus equi: a model of immunopathology. Arch. Med. Vet. 27: 512. [Links] FERNÁNDEZ, A. S.

, J. F. PRESCOTT, V. M. NICHOLSON. Protective effect 1997. Against Rhodococcus equi infection in mice of purified IgG from horses Vaccinated With virulance associated protein (VAP) enriched antigen. Vet. Microbiol. 56: 187-192. [Links] Fuhrmann, C. , C.

Lämmler. 1997. Characterisierung von Rhodococcus equi Mensch und Pferd von isolaten. Berliner Münch. Tierarztliche Wochenschr. 110: 5459. [Links] Gustafsson, A. , V. BAVERUD, A. GUNNARSSON, M. H. Rantzien A.

Lindholm, A. , FRANKLIN, M. HORN-Rantzien. 1997. The association of erythromycin ethylsuccinatte With acute colitis in horses in Sweden. Equine Vet. J. 29: 314318. [Links] Higuchi, T. , S. TAHARAGUCHI, A. HASHIKURA, S.

Hagiwara, C. GOJO, S. Satoh M. Yoshida, S. TAKAI. 1998. Physical and serological examinations of foals at 30 and 45 days of age for early diagnosis of Rhodococcus equi infection on endemically infected farms. JAVMA 212: 776 781. [Links] HOLT, J. G. , N. R.

KRIEG, P. H. A. Sneath, J. T. Staley, S. T. WILLIAMS. 1994. Bergey’s Manual of Determinative Bacteriology. 9th Edit. Williams \x26amp; Wilkins, Baltimore, USA. [Links]

Knottenbelt, D. C. 1993. Rhodococcus equi infection in foals: a report of an outbreak on a thoroughbred stud in Zimbabwe. Vet. 132 Rec. 7985. [Links] LOPEZ, A. 1995. Respiratory System. Quoted in: CARLTON, W. W.

and M. D. Mc GAVIN. Thomson’s Special Veterinary Pathology. 2nd Edit. Mosby, St. Louis. [Links] NAY, T. S. 1996. Extra-pulmonary Rhodococcus equi in a foal throroughbred. Dog.

Vet. J. 37: 623624. [Links] NORDENGRAHN, A. , M. RUSVAI, M. MERZA, J. EKSTROM, B. Morein, S. Belak. Equine herpesvirus 1996. Type 2 (EHV-2) as a predisposing factor for Rhodococcus equi pneumonia in foals: prevention of the disease bifactorial With EHV-2 immunostimulating complexes.

Vet. Microbiol. 51: 5568. [Links] WALLS, E. , V. CUBILLOS. 1995. Manual of Necropsy in Domestic Animals. Faculty of Veterinary Science, Universidad Austral de Chile, Valdivia. [Links] PRESCOTT, J. F.

Rhodococcus equi 1991: an Animal and human pathogen. Clinical Microbiology Reviews 4: 20-34. [Links] SOEDARMANTO, I. , R. OLIVEIRA, CH. Lämmler, H. DURRLING. 1997. Identification and epidemiological relationship of Rhodococcus equi isolated from cases of lymphadenitis in cattle. Zbl. Bak. 286: 457467.

[Links] SOEDARMANTO, I. , W. Zhicai, A. SETYAMAHANANI, CH. Lämmler. 1998. Pheno- and genotyping of Rhodococcus equi isolated from faeces of healthy horses and cattle. Res. Vet. Sci. 64: 181185. [Links]

Takai S. , Y. IMAI, N. Fukunaga, Y. UCHIDA, KAMISARA K. , Y. Sasaki, S. TSUBAKI, T. Sekizaki. 1995. Identification of virulence-associated antigens and plasmids from Rhodococcus equi in Patients With AIDS. J. Infect.

Dis. 172: 13061311. [Links] VAN Kruiningen, H. 1995. Gastrointestinal System. Quoted in: CARLTON, W. W. and M. D. Mc GAVIN. Thomson’s Special Veterinary Pathology. 2nd Edit.

Mosby, St. Louis. [Links] VIVRETTE, S. 1992. The diagnosis, treatment, and prevention of Rhodococcus equi pneumonia in foals. Vet. Med. 87: 144-149. [Links] YAGER, J. A. 1987.

The pathogenesis of Rhodococcus equi pneumonia in foals. Vet. Microbiol. 14: 225232. [Links]

PayPerView: VII. New clinical contributions to the clarification of the difference between dermatosis dysmenorrhoica, herpes

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The three-month injection for the prevention

What is Depo-Provera and how is it administered? As the name suggests, the Depo-Provera is administered every 12 weeks in the buttocks or upper arm. The injection should be carried out within the first 5 days of a period of a doctor. Because of this progesterone depot in the muscle, a small amount of the hormone is then continuously released into the blood and transported to the uterus to the ovaries with the blood. The effect begins immediately after the injection, subsequent injections are the 14 days before the expiration of the 3 months, ie 10 to 12 weeks, necessary. How safe is it? The syringe is a safe method of contraception. However, the effective protection depends, as with all hormone preparations the woman’s age and the implementation dates for a booster injection. For optimal use, the contraceptive effectiveness of Depo-Provera is 99% in the first 2 years. Then the security falls Information Statistics English a little, to 97%. Nevertheless, the contraceptive injection is considered one of the safest methods of contraception. This is in particular the fact that the risk of application failure is extremely low. advantages

The Depo-Provera is especially suitable for women who other estrogen-containing preparations may not take, but prefer a lasting hormonal contraceptive method. It is also for women an advantage that can not keep a regular intake time of the pill (such as shift work or many time shifts by traveling). Due to the constant action of more than 3 months of spontaneous sex is possible and not worry about a possible pregnancy you have to do during this time. The injection offers the same advantages as the pill: it blunts the bleeding or may even lead to exposing them for some time. In addition, the pain may be lower and the risk of uterine cancer is lowered during the period. Unlike the pill, the effect is not affected by vomiting. Consequently, Depo-Provera and women is recommended to those suffering from chronic stomach and intestinal diseases. Since the injected hormones also thicken cervical mucus (cervical mucus), not only sperm but also bacteria are prevented from further entering the Gebämutter. This results in an additional protection against Beckenentzündüngen (pelvic inflammatory disease, PID). PID can lead to ectopic pregnancy (pregnancy outside the Gebämutter) or even cause a miscarriage. disadvantages The main drawback of this the three-month injection is that they can not be undone once the injection has been administered. The effect and possible side effects are not reversible for the next 3 months.

In addition, it may take a little longer, until the full fertility is made after the end of treatment. In most cases this is the case after 2-3 months, but it may also sometimes take up to a year. Although side effects are rare, it may still, as with all other hormone-containing contraceptive methods also cause headaches, come dragging in the chest, weight gain, mood swings, stomach problems and acne. Although menstrual periods weaker by injecting generally, some women make to the contrary experience. In these cases, it can lead to long-lasting interim and spotting come, so usually no subsequent injections are desired. Other risks Will the Depo-Provera for a long time (over 2 years) applied, the risk can increase to osteoporosis. This process is reversible and the bone density increases again, when the injections are stopped. This is also the reason why young women and girls is not recommended under 18 years of Depo-Provera. In these cases, which shall not be unnecessarily impaired not yet fully completed, bone growth, which is why other contraceptive methods are preferable. Contraindications From a Depo-Provera is not recommended if: You are pregnant;

They had just one birth behind (they wait with an injection of at least 6 weeks); You have breast cancer; You have bleeding between periods; You had a heart attack or stroke in the past few months; They suffer from high blood pressure, blood clots, diabetes or liver disease;

“The men are quietly spend the door for me”

A woman with real entertainer qualities: Eleven years was Ina Müller one half of the cabaret duo Queen Bee. Now she’s solo success. In NDR television the 42-year-old “Inas north”, the music and Talkmix “Inas Nacht” and the dome show moderated “Land \x26amp; Love”, which comes much more charming than the RTL-equivalent “Farmer Wants a Wife”. With her tour for the album “Female. Single. 40” the singer Müller ensures out arenas, and also their Low German songs and books a large audience. Morgenpost Online: Mrs Müller, currently you are working pretty much for television. Ina Müller: Yes, and if it then would what I want, I would still make a lot more television. This is extremely difficult to repeatedly decide there for or against something. Morgenpost Online: 320 days a year. Where do you get the energy? Müller: I do not know. Nothing is not to much, if I’m honest.

I pull these boots now since a half years through and can give up anything, because everything makes so’n fun. One just needs to give up his private life, but that is necessary also ‘ne time. In addition, I believe that also give me the field of energy. Morgenpost Online: About your cheeky northern Germany Schnack laugh in southern Germany. Assuming ARD program director Guenter Struve offers a show in the First. What would you say? Müller: I would say yes. Morgenpost Online: Short and sweet. Müller: Yes, because I find not only the first great, but Struve also nice. I would say yes, if I like the concept. And immediately no, if you do not like me. Morgenpost Online: You are the fourth of five daughters on a farm in the district of Cuxhaven grown. Is this where your love for Low German language?

Müller: The love of the Low German language came with the mother’s milk, because we have spoken at home only Platt. In between I’ve Low German but hated in puberty that was really bad. But at some point I have to stage this love found again when I realized how great the audience finds Low German songs. That was a bit of a passion. Low German are simply my roots, and Low German is simply ‘ne eerily beautiful language. Can also be much better singing than High German. A Plattdüsk album I could write itself. Morgenpost Online: And High German? Müller: High German I’ll get just the help of Frank Ramond. Because: I can not. I think I’m also not quite able slimy lyrics to sing by myself. When I wrote someone else ‘nen slimy text, then I say: But he is beautiful. And sing the well.

But his own texts, that is, I believe, to close. My own texts that throw ‘I always be gone. I write ‘the evening, and then les I the morning and thinking’ ogottogottogott. What is alittle bit unfortunate because I would be perhaps more courageous. Morgenpost Online: Here Are you really so brave. Approximately in your dome show “Land \x26amp; Love”, where you always meet the candidates very easy and natural. Is that just your income that the candidates come out of itself, or is placed on their repartee at the casting value? Müller: Absolutely not. When casting is taken extremely sure that the mix is ​​right. We would not take three older men or three younger men. There has to be a wife. The market is full with women around 50 who are looking for ‘nen man. Whether encouraging village or in the city.

But our candidates must also have a real chance to find someone. We’re doing but no action. And if even the cows have to be carried about, we also help without the camera is on. Morgenpost Online: Was that your idea that women join the men looking for? Müller: That was all clear from the outset, it was not spoken. Morgenpost Online: Have you ever been with RTL “Farmer Wants a Wife” seen? Müller: No, but not because I did not want to watch, but because I was never home. I have recently said to someone, I will watch Saturday’s times. Until I was informed that comes not Saturday, but Monday. Morgenpost Online: The rate increases from week to week. At the beginning of the new season the show was okay, but in the meantime but the whole thing seems very artificial. Müller: You watching the because because there you because you want to understand the phenomenon has not it? Morgenpost Online: Uh, for professional reasons.

Müller: If I see the success of the mission, I believe, it will run with the dome program similar to the cooking shows. Morgenpost Online: The ZDF is planning next year’s program “Ossi seeking women” to start. Müller: I know that there is research which groups are also difficult to convey. It should be there: corpse washers and prostitutes. I think we can look forward to some television formats next year. I always like to say this sentence: Long live the music. (laughs out loud) Morgenpost Online: Exactly, music! In your songs you often broach role models. In the song “Stupid kicks well” as you sing simple men with simple-hearted, “somewhat underexposed, but large and neat, which are not as bright, but really good in bed”. Müller: This is of course completely exaggerated. It should provoke, so you say: What is the mood for that spins well. I can imagine your next question to me now: Do you really want that the men are back?

Morgenpost Online: I have not asked. Müller: What would you have asked? Morgenpost Online: Do you think that us men often the head is in the way? Müller: No, I think that we often are women in your way. I think we have not then we expressed clearly enough, as is said: Awake to a difference, but will be a bit more like us, but not too much as we do. Of course, I do not want to back the Neanderthal man, who pulls the woman by the hair through the cave. but I want to resume a normal male-female ratio of flirting. The are calm again stopping the door for me. When I get up in the train ‘, then to the bide me, help me and rausstellen the suitcase. The man sometimes I’m in his role a bit sorry. I think he knows himself no longer, as it should be. Morgenpost Online: As a guest of the WDR broadcast “Zimmer frei” They have recently outed as a football fan. My favorite club is Bayern Munich.

And as North German? Muller: Bayern Munich has thus revealed that I have lived in Munich ‘. I like Uli Hoeness. I’ve always doing photos when I met the whole team in Bremen ‘. I with Franck Ribéry. May I show you the picture, I’m so proud of it. Morgenpost Online: Like. Müller: And you have HSV-Fan? (The interview took place in Hamburg. ) Morgenpost Online: Exactly, and how it is with you with the HSV? Müller: I think the HSV also quite good. But now let’s see (Müller shows the photo on which she smiles while Ribéry beside her – as usual – straight face contorts).

See how excited I am? If the so happy and running around to the door and with his feet deflects to the right and left, then I like the way. I’m so glad that takes my pain from Mehmet Scholl’s farewell. Morgenpost Online: Coming back to the topic of men. You once said: Saturdays together Macchiato on the market, then together ‘nen bar, then everyone alone for sports, then back together on the couch – it was not sexy and make love broken. Do you not even on Saturdays together see the “Sports Watch”? Müller: Yes, but I would previously not have been on the market together. I have gladly pulled so: Rüber senator (the restaurant Zum Alten Senator in Hamburg is miller hangout), bring two fresh draft beer and cheer sofa together “Sports Watch” movies. That I find beautiful. The rest is just not for me. So about the guy is wearing the wicker basket, and you walk through the organic market to buy good food. There are so couples-attitudes that have never suited me and be my never lie. Contraction in itself I think is a very difficult process.

Rather, I believe that we should deal with it, to keep the love alive. And I think that does not work by getting too close. Morgenpost Online: Another quote from you: “At the age I would have so much money that I can pay a young man who brings me drinks and lovingly caresses the face. ” Their idea of ​​family replacement in old age? Müller: So, I as a woman over 40 who are aware no family in the sense children will, of course I also dream of someday find the man I love so great and where everything works great. This dream must have one, otherwise one could indeed kill also. As for the future: No one knows what it takes, no one knows what the euro is still worth. Why do I with my money so three piles. One thing is for old age, and which I hope to be able to pay someone brings me a drink. Jung I have only said that because you are looking, I think the contact with people who are simply younger. And emphasize his face, well, what do you expect with 75 out of life, if we are honest, except that you have someone stroking his face? Men see that, I think, sometimes different. The can imagine at that age well, get started again.

I’m realistic.