University Institute of the Hospital Italiano de Buenos Aires

Viral infections such as bio-anthropological markers of human migration events The research aims to deepen the knowledge of the ethnic diversity of contemporary Argentina population, through the study of evolution and genotypic characterization of Latin American strains of HTLV 1/2, HHV-7 and HHV-8 associated with migratory events ancestral humans. The project by Dr. Trinks and Lic. María Laura Hulaniuk (doctoral fellow at the Institute of Basic Sciences and Experimental Medicine, University Institute). This project, in collaboration with the Genetic Fingerprinting (SHDG) of the Faculty of Pharmacy and Biochemistry, University of Buenos Aires, led by Dr. Daniel Corach, part of the idea that viruses are microorganisms that have accompanied the man throughout human development, and this migration have also evolved. By studying the evolution of these viruses and their distribution throughout the planet, you can trace the pattern of human migrations. “They developed techniques to map or trace the ancestry of modern Argentina evolution, studying markers you are in our DNA. If we add what they do to us what we do here at the Institute from the point of view of the virus- we will be able to increase the knowledge of the origin of the current population Argentina “explains Dr. Trinks and broad” work with virus they have certain characteristics, among which, we are working at this moment-and for which we already have some results presented in congresos- is the Herpes virus type 8 “. The Herpes Virus Human type 8 (HHV-8) is the cause of Kaposi’s sarcoma, a malignant tumor that is, a form of cancer, which may appear on the skin or the viscera and, today, it is closely associated immunosuppression, mainly related to Acquired Immune Deficiency Syndrome (AIDS). It has also been shown to have a global geographic distribution and is most prevalent in African and Latin American populations.


Unfortunately, in our country there is no data on the prevalence of this virus in the population. “One of the first steps of this project was to study groups of blood donors from the Italian Hospital and across the country, to determine the prevalence of this type of herpes virus. We found truly surprising results: in the northwest region in Jujuy specifically, we found a high prevalence of 12. 3% in units of blood were transfused. ” This virus, which is not normally It tests in blood banks is being analyzed samples from infected patients provided by the Department of Pathology of infected patients in the Italian Hospital, to study its variability and compare it with the ancestral population, through molecular methods. The contributions of the research project The project has two input lines: on the one hand, the ancestral population since the Argentina population is extremely diverse and unique composition worldwide for the high degree of mixing it presents. For anthropologists, forensic or even those engaged in forensic genetics, is a great addition to using different resources, and in this case the virus bring its action to further deepen understanding of the highly complex having the composition of the population. On the other hand is relevant from the point of view of the virus, “this is a virus that our country has not been extensively studied. Then we are moving this way. For virology or infectious diseases to determine the prevalence of different virus the different regions of our country and is also important from the point of view of public health because it allows doctors to know what we are are facing in today’s society “emphasizes Dr. Trinks. the subsidy

The grant helped mainly for the purchase of reagents, which allowed us to make rapid progress on the project. It is able to manage the flow of financial resources allowed them to speed up administrative processes and get faster reagents. “It allowed us to move much faster in the project have the reagents. We achieved several publications in congresses and we are already writing the first manuscript to send to publish the project, so it really was an important help “develop Dr. Trinks and explains how the investigation continues” we intend to achieve two publications with our work with the Herpesvirus kind. At the moment, we have finished the job of first publication, but we continue to work with patient samples provided by the Department of Pathology “. In the future, it is thought also expand to other viruses, such as herpes type 7 human virus (HHV 7) or human T lymphotropic virus type 1 and 2 cells (HTLV 1/2) which also serve as markers of human migrations. To learn more about the research, download here the summary presented at the XI Argentine Congress of Virology. open call Currently and until July 31 can be applied to a new edition of research grants University Institute Hospital Italiano. – “Grant Dr. Enrique Beveraggi” to research related to subjects of the Clinical Cycle – “Grant Dr.

Ruben Gutman” Research related to matters of Biomedical Cycle – “Grant Dr. Enrique Caruso” to research related to Education for Health Professionals – “Grant Dr. Alejandro Ayzaguer” the oriented Clinical Research Imaging More info: http://goo. gl/uKGJMn